词条 | Coenzyme F420-0:L-glutamate ligase |
释义 |
| Name = Coenzyme F420-0:L-glutamate ligase | EC_number = 6.3.2.31 | CAS_number = | IUBMB_EC_number = 6/3/2/31 | GO_code = | image = | width = | caption = }}Coenzyme F420-0:L-glutamate ligase ({{EC number|6.3.2.31}}, CofE-AF, MJ0768, CofE) is an enzyme with systematic name L-glutamate:coenzyme F420-0 ligase (GDP-forming).[1][2] This enzyme catalyses the following chemical reaction GTP + coenzyme F420-0 + L-glutamate GDP + phosphate + coenzyme F420-1 This protein catalyses the successive addition of two glutamate residues to cofactor F420 by two distinct and independent reactions. References1. ^{{cite journal | vauthors = Li H, Graupner M, Xu H, White RH | title = CofE catalyzes the addition of two glutamates to F420-0 in F420 coenzyme biosynthesis in Methanococcus jannaschii | journal = Biochemistry | volume = 42 | issue = 32 | pages = 9771–8 | date = August 2003 | pmid = 12911320 | doi = 10.1021/bi034779b }} 2. ^{{cite journal | vauthors = Nocek B, Evdokimova E, Proudfoot M, Kudritska M, Grochowski LL, White RH, Savchenko A, Yakunin AF, Edwards A, Joachimiak A | title = Structure of an amide bond forming F(420):gamma-glutamyl ligase from Archaeoglobus fulgidus -- a member of a new family of non-ribosomal peptide synthases | journal = Journal of Molecular Biology | volume = 372 | issue = 2 | pages = 456–69 | date = September 2007 | pmid = 17669425 | pmc = 2678844 | doi = 10.1016/j.jmb.2007.06.063 }} External links
1 : EC 6.3.2 |
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