词条 | Collier's sign |
释义 |
Collier's sign (also known as Collier's tucked lid sign[1] or posterior fossa stare) is bilateral or unilateral eyelid retraction. It is an accepted medical sign of a midbrain lesion, first described in 1927 by J Collier.[1] With the eyes in the primary position, the sclera can be seen above the cornea, and further upgaze increases the distance between the eyelids and irises.[4] Causes include upper dorsal midbrain supranuclear lesions such as Parinaud's syndrome, 'top of the basilar syndrome', midbrain infarction, neurodegeneration or tumour, multiple sclerosis, encephalitis, and Miller-Fisher syndrome.[6] The cause is thought to be damage to the posterior commissure levator inhibitory fibres which originate in the M-group of neurons.[4] References1. ^J. Collier, Nuclear Ophthalmoplegia with special reference to retraction of the lids and ptosis and to lesions of the posterior commissure. Brain (journal) 1927; 50; 488 - 498. {{subscription required}}[2][3][4]2. ^1 {{cite web|url = http://www.biology-online.org/dictionary/Colliers_sign|title = Colliers sign|publisher = biology-online.org}} 3. ^1 Miyashi M et al., Rinsho Shinkeigaku. 2006 Oct;46(10):712-4 4. ^1 2 {{cite web|title = Supranuclear Paralysis of Upgaze|author = Wray|url = http://content.lib.utah.edu/cdm/singleitem/collection/ehsl-shw/id/41/rec/27}} }}{{neuroscience-stub}}{{eye-stub}}{{med-sign-stub}} 1 : Medical signs |
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