| 词条 | Competition-ChIP |
| 释义 |
Competition-ChIP is variant of the Chip-Sequencing protocol, used to measure relative binding dynamics of a transcription factor (TF) on DNA.[1] Since TF occupancy measures are thought to be a poor predictor of TF function at a given locus, Competition-ChIP is much more strongly linked to function than occupancy. The technique was originally developed in Jason D. Lieb's Lab in 2011. References1. ^{{cite journal|title=Genome-wide measurement of protein-DNA binding dynamics using competition ChIP|url=https://www.researchgate.net/publication/237822177_Genome-wide_measurement_of_protein-DNA_binding_dynamics_using_competition_ChIP|doi=10.1038/nprot.2013.077|first1=Jason D.|last1=Lieb|journal=Nat. Protoc.|date=2013|volume=8|issue=7|pages=1337-53}} 2 : Protein methods|Molecular biology techniques |
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