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词条 Costunolide synthase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Costunolide synthase
| EC_number = 1.14.13.120
| CAS_number =
| IUBMB_EC_number = 1/14/13/120
| GO_code =
| image =
| width =
| caption =
}}Costunolide synthase ({{EC number|1.14.13.120}}) is an enzyme with systematic name germacra-1(10),4,11(13)-trien-12-oate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating).[1] This enzyme catalyses the following chemical reaction

germacra-1(10),4,11(13)-trien-12-oate + NADPH + H+ + O2 (+)-costunolide + NADP+ + 2 H2O

Costunolide synthase is a heme-thiolate protein (P-450).

References

1. ^{{cite journal | vauthors = de Kraker JW, Franssen MC, Joerink M, de Groot A, Bouwmeester HJ | title = Biosynthesis of costunolide, dihydrocostunolide, and leucodin. Demonstration of cytochrome p450-catalyzed formation of the lactone ring present in sesquiterpene lactones of chicory | journal = Plant Physiology | volume = 129 | issue = 1 | pages = 257–68 | date = May 2002 | pmid = 12011356 | pmc = 155889 | doi = 10.1104/pp.010957 }}

External links

  • {{MeshName|Costunolide+synthase}}
{{Dioxygenases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 1.14.13

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