| 词条 | Cyanoacetamide |
| 释义 |
| Name = 2-Cyanoacetamide | ImageFile = Cyanoacetamide.svg | ImageSize = 150px | IUPACName = 2-Cyanoacetamide | OtherNames = Malonamide nitrile 3-Nitrilopropionamide |Section1={{Chembox Identifiers | ChemSpiderID_Ref = | ChemSpiderID = 7610 | PubChem = 7898 | InChIKey = | SMILES = N#CCC(=O)N | ChEMBL_Ref = | ChEMBL = | StdInChI_Ref = | StdInChI = 1S/C3H4N2O/c4-2-1-3(5)6/h1H2,(H2,5,6) | StdInChIKey_Ref = | StdInChIKey = DGJMPUGMZIKDRO-UHFFFAOYSA-N | CASNo_Ref = {{cascite|correct|CAS}} | CASNo = 107-91-5 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = YBK38G2YXH | RTECS = | UNNumber = | EINECS = 203-531-8 | KEGG_Ref = | KEGG = |Section2={{Chembox Properties | C=3 | H=4 | N=2 | O=1 | Density = 1.163 g/cm3 | MeltingPtC = 119 to 121 | BoilingPtC = 351.2 |Section7={{Chembox Hazards | ExternalSDS = | EUClass = | MainHazards = | NFPA-H = | NFPA-F = | NFPA-R = | NFPA-S = | GHSPictograms = {{GHS07}} | GHSSignalWord = Warning | HPhrases = {{H-phrases|302|315|319|335}} | PPhrases = {{P-phrases|261|264|270|271|280|301+312|302+352|304+340|305+351+338|312|321|330|332+313|337+313|362|403+233|405|501}} |Section8={{Chembox Related | OtherCompounds = }} 2-Cyanoacetamide is an organic compound. It is an acetic amide with a nitrile functional group. UsesCyanoacetamide is used in spectrofluorimetric methods to determine the activity of antihistamine H1 receptor antagonistic drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride.[1] Preparation2-Cyanoacetamide is prepared from chloroacetic acid via Kolbe nitrile synthesis[2] followed by Fischer esterification and ester aminolysis.[3] See also
References1. ^{{cite journal|last1=Ibrahim|first1=F.|last2=Sharaf El-Din|first2=M. K.|last3=Eid|first3=M.|last4=Wahba|first4=M. E. K.|title=Spectrofluorimetric Determination Of Some H1 Receptor Antagonist Drugs In Pharmaceutical Formulations And Biological Fluids|journal=International Journal of Pharmaceutical Sciences and Research|date=2011|volume=21|issue=8|pages=2056–2072|doi=10.13040/IJPSR.0975-8232.2(8).2056-72}} {{organic-compound-stub}}2. ^{{cite journal|last1=Inglis|first1=J. K. H.|title=Ethyl Cyanoacetate|journal=Organic Syntheses|date=1928|volume=8|page=74|doi=10.15227/orgsyn.008.0074}} 3. ^{{cite journal|last1=Corson|first1=B. B.|last2=Scott|first2=R. W.|last3=Vose|first3=C. E.|title=Cyanoacetamide|journal=Organic Syntheses|date=1941|volume=1|page=179|doi=10.15227/orgsyn.009.0036}} 2 : Acetamides|Nitriles |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。