| 词条 | Potassium citrate |
| 释义 |
| ImageFile = Kaliumcitrat V2.svg | ImageSize = 300px | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 464211279 | IUPACName =tripotassium citrate | OtherNames = |Section1={{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 12775 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1200458 | InChI = 1/C6H8O7.3K/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3 | InChIKey = QEEAPRPFLLJWCF-DFZHHIFOAD | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C6H8O7.3K/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = QEEAPRPFLLJWCF-UHFFFAOYSA-K | CASNo_Ref = {{cascite|correct|CAS}} | CASNo =866-84-2 | PubChem =13344 | SMILES = [K+].[K+].[K+].O=C([O-])CC(O)(C([O-])=O)CC(=O)[O-] }} |Section2={{Chembox Properties | Formula =K3C6H5O7 | MolarMass =306.395 g/mol | Appearance = white powder hygroscopic | Odor = odorless | Density = 1.98 g/cm3 | MeltingPtC = 180 | MeltingPt_ref = [1] | BoilingPtC = 230 | BoilingPt_ref = [1] | Solubility = soluble | SolubleOther = soluble in glycerin insoluble in ethanol (95%) | pKa = 8.5 |Section6={{Chembox Pharmacology | ATCCode_prefix = A12 | ATCCode_suffix = BA02 }} |Section7={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = | LD50 = 170 mg/kg (IV, dog) }} Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid with the molecular formula K3C6H5O7. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.28% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. As a food additive, potassium citrate is used to regulate acidity and is known as E number E332. Medicinally, it may be used to control kidney stones derived from either uric acid or cystine. ProductionPotassium citrate is produced by adding potassium bicarbonate or potassium carbonate to a solution of citric acid until effervescence ceases, filtering the solution and evaporating to granulation. UsesPotassium citrate is rapidly absorbed when given by mouth and is excreted in the urine.[2] Since it is an alkaline salt it is effective in reducing the pain and frequency of urination when these are caused by highly acidic urine.[3] It is used for this purpose in dogs and cats, but is chiefly employed as a non-irritating diuretic. Potassium citrate is an effective way to treat/manage gout[4] and arrhythmia,{{medcn|date=May 2013}} if the patient is hypokalemic. It is widely used to treat urinary calculi (kidney stones) and is often used by patients with cystinuria.{{medcn|date=May 2013}} A study of 500 patients with recurrent stones found that it reduced the frequency of stones from 2 per year to a half per year. It is also used as an alkanizing agent in the treatment of mild urinary tract infections such as cystitis.[5] It is also used in many soft drinks as a buffering agent.[6] AdministrationPotassium citrate is usually administered by mouth in dilute aqueous solution. This is because of its somewhat caustic effect on the stomach lining, and the potential for other mild health hazards. References1. ^1 Environmental Health & Safety MSDS Number:P5675 2. ^Medscape on hypocitraturia 3. ^Potassium Citrate for Kidney Stones 4. ^Potassium Citrate 5. ^{{Cite web |publisher = patient.info|url = http://patient.info/medicine/potassium-citrate-for-cystitis|title = Potassium citrate for cystitis}} 6. ^https://www.livestrong.com/article/314839-soft-drinks-with-potassium-citrate/ External links
4 : Food acidity regulators|Citrates|Potassium compounds|E-number additives |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。