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| Name = dATP(dGTP)—DNA purinetransferase
| EC_number = 2.6.99.1
| CAS_number =
| IUBMB_EC_number = 2/6/99/1
| GO_code =
| image =
| width =
| caption =
}}dATP(dGTP)—DNA purinetransferase ({{EC number|2.6.99.1}}) is an enzyme with systematic name dATP(dGTP):depurinated-DNA purine transferase.[1][2] This enzyme catalyses the following chemical reaction
(1) dATP + depurinated DNAdeoxyribose triphosphate + DNA
(2) dGTP + depurinated DNA
The purine residue is transferred on to the apurinic site forming a normal glycosylic bond.
References
1. ^{{cite journal | vauthors = Deutsch WA, Linn S | title = DNA binding activity from cultured human fibrolasts that is specific for partially depurinated DNA and that inserts purines into apurinic sites | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 76 | issue = 1 | pages = 141–4 | date = January 1979 | pmid = 218192 | pmc = 382892 | doi = 10.1073/pnas.76.1.141 }}
2. ^{{cite journal | vauthors = Livneh Z, Elad D, Sperling J | title = Enzymatic insertion of purine bases into depurinated DNA in vitro | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 76 | issue = 3 | pages = 1089–93 | date = March 1979 | pmid = 375225 | pmc = 383194 | doi = 10.1073/pnas.76.3.1089 }}
2. ^{{cite journal | vauthors = Livneh Z, Elad D, Sperling J | title = Enzymatic insertion of purine bases into depurinated DNA in vitro | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 76 | issue = 3 | pages = 1089–93 | date = March 1979 | pmid = 375225 | pmc = 383194 | doi = 10.1073/pnas.76.3.1089 }}
External links
- {{MeshName|DATP(dGTP)---DNA+purinetransferase}}
1 : EC 2.6.99
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