| 词条 | David Ballou |
| 释义 |
| name = David P. Ballou | image = | image_size = | alt = | caption = | birth_date = | birth_place = | death_date = | death_place = | resting_place = | resting_place_coordinates = | residence = | citizenship = American | nationality = American | fields = Biochemistry | workplaces = University of Michigan | alma_mater = Antioch College University of Michigan | thesis_title = | thesis_url = | thesis_year = 1971 | doctoral_advisor = Graham Palmer | academic_advisors = Vince Massey Minor J. Coon | doctoral_students = | notable_students = | known_for = Presteady-state enzyme kinetics methods | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = | signature = | signature_alt = | website = | footnotes = | spouse = Jean Ballou[1] }}David P. Ballou is a professor of biological chemistry at the University of Michigan Medical School in the United States.[1] He is best known for his development of rapid-reaction techniques,[2] including stopped flow and rapid freeze-quench EPR methods,[3] as tools to study the mechanisms of enzymes containing flavin,[4] iron,[5] cobalamin, or pyridoxal phosphate cofactors. Many of these studies were performed in collaboration with other scientists, most often with colleagues at Michigan.[6] BiographyDavid Ballou grew up in Connecticut.[2] He received a B.S. in chemistry from Antioch College in 1965. In 1971, he received a Ph.D. from the University of Michigan under the supervision of Graham Palmer. From 1971-1972, he was a postdoctoral fellow with Vincent Massey and Minor J. Coon at the University of Michigan. He has been a faculty member in the Department of Biological Chemistry at the University of Michigan Medical School since 1972. In 2007, Ballou became a Fellow of the American Association for the Advancement of Science in recognition of his discovery of enzyme intermediates that are involved in biological oxidation reactions.[7] His most cited paper, l, "Oxidative Protein Folding Is Driven by the Electron Transport System",[8] has been cited 311 times according to Google Scholar, and he has contributed to 25 papers having more than 0100 citations each.[9] Books
References1. ^1 {{cite web|url=http://www.biochem.med.umich.edu/?q=ballou |title=David Ballou, Ph.D. |accessdate=2013-10-27 }} 2. ^1 {{cite journal |vauthors=Cheng Z, Zhang J, Ballou DP, ((Williams CH Jr)) |title=Reactivity of Thioredoxin as a Protein Thiol-Disulfide Oxidoreductase |journal=Chemical Reviews |volume=111 |issue=9 |pages=5768–5783 |year=2011 |pmid=21793530 |doi=10.1021/cr100006x | pmc=3212873 }} 3. ^{{cite journal |vauthors=Ballou DP, Palmer GA |title=Practical rapid quenching instrument for the study of reaction mechanisms by electron paramagnetic resonance spectroscopy |journal=Analytical Chemistry |volume=46 |issue=9 |pages=1248–1253 |year=1974 |doi=10.1021/ac60345a034}} 4. ^{{cite journal |vauthors=Ballou DP, Entsch B, Cole LJ |title=Dynamics involved in catalysis by single-component and two-component flavin-dependent aromatic hydroxylases |journal=Biochem. Biophys. Res. Commun. |volume=338 |issue=1 |pages=590–598 |year=2005 |pmid=16236251 |doi=10.1016/j.bbrc.2005.09.081}} 5. ^{{cite journal |vauthors=Gassner GT, Ludwig ML, Gatti DL, Correll CC, Ballou DP |title=Structure and mechanism of the iron-sulfur flavoprotein phthalate dioxygenase reductase |journal=FASEB Journal |volume=9 |issue=14 |pages=1411–1418 |year=1995 |pmid=7589982}} 6. ^{{cite web|url=https://www.ncbi.nlm.nih.gov/pubmed/?term=ballou+dp |title=DP Ballou at Pubmed |accessdate=2013-10-31 }} 7. ^{{cite web|url=http://www.medicineatmichigan.org/magazine/2007/spring/limelight/AAASwelcome.asp |title=AAAS Welcomes Two from Medical School |accessdate=2013-10-27 }} 8. ^Martin Bader, Wilson Muse, David P Ballou, Christian Gassner, James C.A Bardwell, "Oxidative Protein Folding Is Driven by the Electron Transport System", published in Cell Volume 98, Issue 2, p217–227, 23 July 1999 9. ^[https://scholar.google.com/scholar?start=0&q=DP+Ballou&hl=en&as_sdt=0,33] External links
6 : Living people|American biochemists|Fellows of the American Association for the Advancement of Science|University of Michigan alumni|University of Michigan faculty|Year of birth missing (living people) |
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