| 释义 |
- Function
- References
- Further reading
{{Infobox_gene}}Delta(4)-desaturase, sphingolipid 2 is a protein that in humans is encoded by the DEGS2 gene.[1] Function This gene encodes a bifunctional enzyme that is involved in the biosynthesis of sphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase. References 1. ^{{cite web | title = Entrez Gene: Delta(4)-desaturase, sphingolipid 2 | url = https://www.ncbi.nlm.nih.gov/gene/123099 }}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Devlin CM, Lahm T, Hubbard WC, Van Demark M, Wang KC, Wu X, Bielawska A, Obeid LM, Ivan M, Petrache I | title = Dihydroceramide-based response to hypoxia | journal = The Journal of Biological Chemistry | volume = 286 | issue = 44 | pages = 38069–38078 | date = Nov 2011 | pmid = 21914808 | pmc = 3207482 | doi = 10.1074/jbc.M111.297994 }}
- {{cite journal | vauthors = Aouizerat BE, Vittinghoff E, Musone SL, Pawlikowska L, Kwok PY, Olgin JE, Tseng ZH | title = GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease | journal = BMC Cardiovascular Disorders | volume = 11 | pages = 29 | year = 2011 | pmid = 21658281 | pmc = 3141757 | doi = 10.1186/1471-2261-11-29 }}
- {{cite journal | vauthors = Mizutani Y, Kihara A, Igarashi Y | title = Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation | journal = FEBS Letters | volume = 563 | issue = 1-3 | pages = 93–97 | date = Apr 2004 | pmid = 15063729 | pmc = | doi = 10.1016/S0014-5793(04)00274-1 }}
{{refend}}{{NLM content}}{{gene-14-stub}} 2 : Genes|Human proteins |