| 词条 | Densovirinae |
| 释义 |
| taxon = Densovirinae | subdivision_ranks = Genera | subdivision =
}} The Densovirinae[1] are a subfamily of single-stranded DNA viruses in the family Parvoviridae.[2][3] The subfamily currently has 5 recognized genera and 21 species.[4] Densoviruses are known to infect members of insect orders Blattodea, Diptera, Hemiptera, Hymenoptera, Lepidoptera, and Orthoptera, while some viruses infect and multiply in crustceans such as shrimp or crayfish, or sea stars from phylum Echinodermata.[3] VirologyDensoviruses are small (18–26 nanometers in diameter) and non enveloped. Virions are icosahedral in shape with triangulation number (T) = 1. There are 60 copies of the coat protein in the virion. Genomes are about 4–6 kilobases in length and usually contain two or three open reading frames. The 5' open reading frame encodes two nonstructural proteins (NS-1 and NS-2) and the 3' open reading frame encodes two or three capsid proteins (VP1, VP2, VP3). Both the 5' and 3' termini have hairpin loops. If a third open reading frame is present (depends on the genus) it encodes a second non structural protein. The NS-1 protein has a superfamily 3 DNA helicase and an HuH endonuclease motif. These motifs are common in small DNA viruses. The proteins that contain these motifs bind to the viral origins of replication and unwind and nick these origins, allowing access by the host's proteins to the viral genome for replication and transcription. The genome is replicated by a unique rolling hairpin mechanism.[3] TaxonomyFive genera are currently recognized, containing a combined twenty species: Ambidensovirus; type species: Lepidopteran ambidensovirus 1 Brevidensovirus; type species: Dipteran brevidensovirus 1 Hepandensovirus; type species: Decapod hepandensovirus 1 Iteradensovirus; type species: Lepidopteran iteradensovirus 1 Penstyldensovirus; type species: Decapod penstyldensovirus 1 and there is one recognized but unclassified species: Orthopteran densovirus 1; virus name: Acheta domestica mini ambidensovirus References1. ^{{cite web |title=ICTV 10th Report (2018) Densovirinae |url=https://talk.ictvonline.org/ictv-reports/ictv_online_report/ssdna-viruses/w/parvoviridae/1047 }} {{Taxonbar|from=Q5259351}}2. ^{{cite journal | last1 = Cotmore | first1 = SF | last2 = Agbandje-McKenna | first2 = M | last3 = Canuti | first3 = M | last4 = Chiorini | first4 = JA | last5 = Eis-Hubinger | first5 = A | last6 = Hughes | first6 = J | last7 = Mietzsch | first7 = M | last8 = Modha | first8 = S | last9 = Ogliastro | first9 = M | last10 = Pénzes | first10 = JJ | last11 = Pintel | first11 = DJ | last12 = Qiu | first12 = J | last13 = Soderlund-Venermo | first13 = M | last14 = Tattersall | first14 = P | last15 = Tijssen | first15 = P | last16 = and the ICTV Report Consortium | year = 2019 | title = ICTV Virus Taxonomy Profile: Parvoviridae | journal = Journal of General Virology | volume = 100 | issue = 3 | pages = 367–368 | doi = 10.1099/jgv.0.001212| pmid = 30672729}} 3. ^1 2 {{cite web |title=ICTV 10th Report (2018) Parvoviridae|url=https://talk.ictvonline.org/ictv-reports/ictv_online_report/ssdna-viruses/w/parvoviridae }} 4. ^{{cite web|last1=ICTV|title=Virus Taxonomy: 2017 Release|url=https://talk.ictvonline.org/files/master-species-lists/m/msl/7185|accessdate=16 August 2018}} 3 : Densovirinae|Parvoviruses|Virus subfamilies |
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