词条 | D-inositol-3-phosphate glycosyltransferase |
释义 |
| Name = D-inositol-3-phosphate glycosyltransferase | EC_number = 2.4.1.250 | CAS_number = | IUBMB_EC_number = 2/4/1/250 | GO_code = | image = | width = | caption = }}D-inositol-3-phosphate glycosyltransferase ({{EC number|2.4.1.250}}, mycothiol glycosyltransferases, MshA) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:1D-myo-inositol 3-phosphate alpha-D-glycosyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction UDP-N-acetyl-D-glucosamine + 1D-myo-inositol 3-phosphate 1-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + UDP This enzyme catalyses the first dedicated reaction in the biosynthesis of mycothiol. References1. ^{{cite journal | title = The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA) |author1 = Newton, G.L. |author2 =Koledin, T. |author3 =Gorovitz, B. |author4 =Rawat, M. |author5 =Fahey, R.C. |author6 =Av-Gay, Y. | journal = J. Bacteriol. |year = 2003 |volume = 185 |pages = 3476–3479 |pmid = 12754249 | doi = 10.1128/JB.185.11.3476-3479.2003 | issue = 11 | pmc = 155378}} 2. ^{{cite journal | title = Biochemistry of the initial steps of mycothiol biosynthesis |author1 = Newton, G.L. |author2 =Ta, P. |author3 =Bzymek, K.P. |author4 =Fahey, R.C. |journal = J. Biol. Chem. |year = 2006 |volume = 281 |pages = 33910–33920 |pmid = 16940050 | doi = 10.1074/jbc.M604724200 | issue = 45}} 3. ^{{cite journal | title = Structural and enzymatic analysis of MshA from Corynebacterium glutamicum: substrate-assisted catalysis |author1 = Vetting, M.W. |author2 =Frantom, P.A. |author3 =Blanchard, J.S. |journal = J. Biol. Chem. |year = 2008 |volume = 283 |pages = 15834–15844 |pmid = 18390549 | doi = 10.1074/jbc.M801017200 | issue = 23 | pmc = 2414306}} External links
1 : EC 2.4.1 |
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