Don Gross may refer to:

• Don Gross (baseball) (1931–2017), pitcher for Cincinnati and Pittsburgh
• Don Gross (footballer) (born 1947), former VFL footballer for Essendon

• 2nd Royal Fusiliers
• 2nd Rugby-Bundesliga
• 2nd Saeima
• 2nd SA Infantry Regiment
• 2nd Saturn Awards
• 2nd Scottish independence referendum
• 2nd sector of Marseille
• 2nd Security Force Assistance Brigade
• 2nd Serres Regiment
• 2nd Siberian Army Corps
• 2nd Siberian Rifle Corps
• 2nd Siberian Rifle Division (Russian Empire)
• 2nd (Sidmouth) Devonshire Artillery Volunteer Corps
• 2nd Siege of Theodosia
• 2nd Signal Brigade (United States)
• 2nd Silesian War
• 2nd Smirnovka
• 2nd Sofia Infantry Regiment
• 2nd South African Infantry Regiment
• 2nd South Carolina Infantry
• 2nd South Carolina Infantry Regiment
• 2nd (South Middlesex) Rifle Volunteer Corps
• 2nd Spanish Armada
• 2nd Special Squadron (Japanese Navy)
• 2nd Spetsnaz Brigade