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Eccles is a surname. Notable people with the surname include: - Ambrose Eccles (died 1809), Irish Shakespearean scholar
- Clancy Eccles (1940–2005), Jamaican musician
- David Eccles (businessman) (1849–1912), American businessman who became Utah's first multimillionaire
- David Eccles, 1st Viscount Eccles (1904–1999), British Conservative politician
- George S. Eccles (1900–1982), businessman and philanthropist
- Graham Eccles, rugby league footballer of the 1960s, '70s and '80s for Leeds, and Wakefield Trinity
- Henry Eccles (composer) (1670–1742),
- Henry E. Eccles (1898–1986), Rear Admiral in the United States Navy
- James Eccles (1838–1915), English mountaineer and geologist
- J. R. Eccles (1874–1956), English schoolmaster and author
- John Carew Eccles (1903–1997), Australian neurophysiologist, nobel laureate
- John Eccles (1668–1735), British composer
- Marriner Stoddard Eccles (1890–1977), U.S. banker, economist, and Chairman of the Federal Reserve
- Mary Eccles, Viscountess Eccles (1912–2003), book collector and scholar
- Solomon Eccles (1618–1683), English musician
- Spencer Eccles (born 1934), a prominent financier and philanthropist in Salt Lake City, Utah
- Tony Eccles (1970), English darts player
- William Henry Eccles (1875–1966), British physicist
- William J. Eccles (1917–1998), historian of Canada
{{surname|Eccles}} 1 : English toponymic surnames |