“Effector-triggered immunity”的意思、由来-开放百科全书

The innate immune system is common to all multicellular organisms and forms the first line of defense against pathogens. Infected cells recognize that they are under attack by detecting the pathogen directly through the Pathogen Associated Molecular Patterns (PAMPS) which bind with the Pattern Recognition Receptors (PRR) on the host cells. Host cells also recognize the pathogen through effector-triggered immunity,^[4] whereby the host cells are alerted to the pathogen by the associated damage caused by pathogenic toxins or effectors.

1. ^{{cite journal|last1=Spoel|first1=SH|title=How do plants achieve immunity? Defence without specialized immune cells.|journal=Nature Reviews Immunology|date=February 2012|doi=10.1038/nri3141|pmid=22273771|volume=12|pages=89–100}}
2. ^{{cite journal|last1=Gassmann|first1=Walter|last2=Bhattacharjee|first2=Saikat|title=Effector-Triggered Immunity Signaling: From Gene-for-Gene Pathways to Protein-Protein Interaction Networks|journal=Molecular Plant-Microbe Interactions|volume=25|issue=7|pages=862–868|doi=10.1094/MPMI-01-12-0024-IA}}
3. ^{{cite journal|last1=Stuart|first1=Lynda M.|last2=Paquette|first2=Nicholas|last3=Boyer|first3=Laurent|title=Effector-triggered versus pattern-triggered immunity: how animals sense pathogens|journal=Nature Reviews Immunology|date=15 February 2013|volume=13|issue=3|pages=199–206|doi=10.1038/nri3398|pmc=4121468}}
4. ^{{cite journal|last1=Rajamuthiah|first1=Rajmohan|title=Effector triggered immunity: Activation of innate immunity in metazoans by bacterial effectors|journal=Virulence|date=May 2014|doi=10.4161/viru.29091|pmc=4189875|volume=5|pages=697–702|pmid=25513770}}

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