| 词条 | Enterococcus malodoratus |
| 释义 |
| color = lightgrey | name = Enterococcus malodoratus | regnum = Bacteria | divisio = Firmicutes | classis = Bacilli | ordo = Lactobacillales | familia = Enterococcaceae | genus = Enterococcus | species = E. malodoratus | binomial = Enterococcus malodoratus | binomial_authority = Collins et al. 1984 }}Enterococcus malodoratus is a species of the Enterococcus genus and a gram positive bacteria capable of opportunistic pathogenic response. These microbes have a thick polypeptide layer.[1] Enterococcus can be found in the gastrointestinal tracts of humans and other mammals. In a study on the enterococcal flora of swine, E. malodoratus was found in the intestines and feces. It was not identified within the tonsils of swine, nor within cats, calves, dogs, horse, or poultry.[2] The name "malodoratus" translates to "ill smelling".[1] PhysiologyE. malodoratus is a nonmotile, facultatively anaerobic microbe, as well as a chemoorganotroph with fermentative metabolism.[1][3] The cells are coccoid in structure, found mostly in pairs or short streptococcus chains. Unlike many other Enterococcus species, E. malodoratus does not usually grow at 45 degrees Celsius, nor does it survive heating at 60 degrees Celsius for 30 minutes. It is nonpigmented. E. malodoratus does not produce methylcarbinol [1] or hydrolyze arginine.[4] In carbohydrate and raffinose broths, E. malodoratus forms acid.[4] It does not form endospores thus separating it from bacilli and clostridia species.[3]PathologyThe Enterococcus genus is "capable of inducing platelet aggregation and tissue factor-dependent fibrin production, which may be relevant to the pathogenesis of enterococcal endocarditis".[5] The microbe is frequently the cause of hospital-acquired noscomial infections, bloodstream infections, and urinary tract infections in its host. Though a normal part of the biota of the intestinal tract of humans and other mammals, Enterococci can also survive for lengths of time with adhesion to environmental surfaces; thus contributing to transmission and possible contagion between hosts.[6] The genus has also been proven to survive desiccation.[3] In general, the inhospitable, acidic, and competitive environment of the gastrointestinal tract limits the spread of enterococci. However, it is often during the early stages of a medical intervention that the enterococci can successfully move and colonize beyond the neutral area near the colon.[3] Diagnosis/identificationDNA methods have been used by researchers to correctly identify specific species within the Enterococcus genus. Using the chaperonin 60 gene (Cpn60), specific species of DNA sequencing can be distinguished in the ~600-bp region. It is imperative to correctly distinguish between Enterococcus species, as some species have been found to be resistant to some drug therapies. In fact, the Enterococcus genus has become important in the study of super infections and pathogenic resistance to antibiotics. E. malodoratus, specifically, has not yet been found to have developed that resistance.[7] HistoricalUntil 1984, all Enterococcus species were considered part of the genus Streptococcus. It was during the 1980s that studies on fatty acid composition, nucleic acid hybridization, and comparative oligonucleotide cataloguing of 16s RNA showed the significant differences between enterococci and streptococci.[8] The differences were enough to establish Enterococcus as a genus of its own. Each species within the enterococci category was reclassified, including E. malodoratus – originally known as S. faecalis subsp. malodoratus.[1] References1. ^1 2 3 4 {{cite journal|last1=Collins|first1=M. D.|last2=Jones|first2=D.|last3=Farrow|first3=J. A. E.|last4=Kilpper-Balz|first4=R.|last5=Schleifer|first5=K. H.|title=Enterococcus avium nom. rev., comb. nov.; E. casseliflavus nom. rev., comb. nov.; E. durans nom. rev., comb. nov.; E. gallinarum comb. nov.; and E. malodoratus sp. nov.|journal=International Journal of Systematic Bacteriology|volume=34|issue=2|year=1984|pages=220–223|issn=0020-7713|doi=10.1099/00207713-34-2-220}} 2. ^{{cite book |last=Gilmore |first=Michael |date=2002 |title=Enterococci: Pathogenesis, Molecular Biology, and Antibiotic Resistance |url= |location= Washington, D.C.|publisher= ASM Press|pages= 57–58|isbn= 1-55581-234-1 }} 3. ^1 2 3 {{cite book |last=Holt |first=John |date=1994 |title=Bergey’s Manual of Determinative Bacteriology |url= |location= Baltimore|publisher= Williams & Wilkins|pages= 528–539|isbn= 0-683-00603-7}} 4. ^1 {{cite web |url= https://www.ncbi.nlm.nih.gov/books/NBK190427/ |title= Enterococcus Diversity, Origins in Nature, and Gut Colonization|last1= Lebreton|first1= Francois|last2= Willems|first2= Rob|date= 2 Feb 2014|website= National Center for Biotechnology Information |publisher= |accessdate=1 July 2014}} 5. ^{{cite journal |last= Johnson|first=Alan |date=1994 |title=The pathogenicity of enterococci |url= http://jac.oxfordjournals.org/content/33/6/1083.full.pdf+html|journal= Journal of Antimicrobial Chemotherapy|publisher= |volume= 33|issue= |pages= 1083–1089|doi= 10.1093/jac/33.6.1083 |accessdate=1 July 2014}} 6. ^{{cite web |url=http://emedicine.medscape.com/article/216993-overview |title= Enterococcal Infections|last1= Fraser|first1= Susan|date=30 June 2014 |website= Medscape|publisher= |accessdate=1 July 2014}} 7. ^{{cite journal |title=Identification of Enterococcus Species and Phenotypically Similar Lactococcus and Vagococcus Species by Reverse Checkerboard Hybridization to Chaperonin 60 Gene Sequences|last1= Goh|first1= Swee Han|last2= Facklam|first2= Richard |date=November 2000 |journal= Journal of Clinical Microbiology|pmc=87524 |pmid=11060051 |volume=38 |pages=3953–9}} 8. ^{{Citation |last1= Sood|first1=Sema |last2= Malhotra |first2=Meenakshi |year= 2008|title= Enterococcal infections and antimicrobial resistance|publisher= Department of Microbiology, All India Institute of Medical Sciences |publication-place= New Delhi, India |pages= 111–121|url= http://icmr.nic.in/ijmr/2008/august/0804.pdf |accessdate=1 July 2014 }} Further reading
External links
2 : Enterococcus|Bacteria described in 1984 |
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