词条 | Exaprolol |
释义 |
| ImageFile = Exaprolol.svg | ImageSize = 200px | ImageAlt = | IUPACName = 1-(2-Cyclohexylphenoxy)-3-(propan-2-ylamino)propan-2-ol | OtherNames = Esprolol |Section1={{Chembox Identifiers | CASNo = 55837-19-9 | PubChem = 65485 | ChemSpiderID = 58934 | InChI=1S/C18H29NO2/c1-14(2)19-12-16(20)13-21-18-11-7-6-10-17(18)15-8-4-3-5-9-15/h6-7,10-11,14-16,19-20H,3-5,8-9,12-13H2,1-2H3 | InChIKey= ABXHHEZNIJUQFM-UHFFFAOYSA-N | SMILES = CC(C)NCC(COC1=CC=CC=C1C2CCCCC2)O}} |Section2={{Chembox Properties | C=18 | H=29 | N=1 | O=2 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}Exaprolol is a beta-adrenoceptor antagonist.[1] SynthesisReferences1. ^{{cite journal|pmid=17961850|year=2008|last1=Van Waarde|first1=A|last2=Doorduin|first2=J|last3=De Jong|first3=JR|last4=Dierckx|first4=RA|last5=Elsinga|first5=PH|title=Synthesis and preliminary evaluation of (S)-11C-exaprolol, a novel beta-adrenoceptor ligand for PET|volume=52|issue=4–5|pages=729–33|doi=10.1016/j.neuint.2007.09.009|journal=Neurochemistry International}} {{Adrenergics}}{{organic-compound-stub}}{{pharma-stub}}2. ^{{cite journal|pmid=8056|year=1976|author1=Carissimi|first1=M|title=Basic ethers of cyclohexylphenols with beta-blocking activity: Synthesis and pharmacological study of exaprolol|journal=Arzneimittel-Forschung|volume=26|issue=4|pages=506–16|last2=Gentili|first2=P|last3=Grumelli|first3=E|last4=Milla|first4=E|last5=Picciola|first5=G|last6=Ravenna|first6=F}} 6 : Beta blockers|Isopropyl compounds|Alcohols|Amines|Phenol ethers|Cyclohexanes |
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