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词条 Exaprolol
释义

  1. Synthesis

  2. References

{{Chembox
| ImageFile = Exaprolol.svg
| ImageSize = 200px
| ImageAlt =
| IUPACName = 1-(2-Cyclohexylphenoxy)-3-(propan-2-ylamino)propan-2-ol
| OtherNames = Esprolol
|Section1={{Chembox Identifiers
| CASNo = 55837-19-9
| PubChem = 65485
| ChemSpiderID = 58934
| InChI=1S/C18H29NO2/c1-14(2)19-12-16(20)13-21-18-11-7-6-10-17(18)15-8-4-3-5-9-15/h6-7,10-11,14-16,19-20H,3-5,8-9,12-13H2,1-2H3
| InChIKey= ABXHHEZNIJUQFM-UHFFFAOYSA-N
| SMILES = CC(C)NCC(COC1=CC=CC=C1C2CCCCC2)O}}
|Section2={{Chembox Properties
| C=18 | H=29 | N=1 | O=2
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = }}
}}Exaprolol is a beta-adrenoceptor antagonist.[1]

Synthesis

References

1. ^{{cite journal|pmid=17961850|year=2008|last1=Van Waarde|first1=A|last2=Doorduin|first2=J|last3=De Jong|first3=JR|last4=Dierckx|first4=RA|last5=Elsinga|first5=PH|title=Synthesis and preliminary evaluation of (S)-11C-exaprolol, a novel beta-adrenoceptor ligand for PET|volume=52|issue=4–5|pages=729–33|doi=10.1016/j.neuint.2007.09.009|journal=Neurochemistry International}}
2. ^{{cite journal|pmid=8056|year=1976|author1=Carissimi|first1=M|title=Basic ethers of cyclohexylphenols with beta-blocking activity: Synthesis and pharmacological study of exaprolol|journal=Arzneimittel-Forschung|volume=26|issue=4|pages=506–16|last2=Gentili|first2=P|last3=Grumelli|first3=E|last4=Milla|first4=E|last5=Picciola|first5=G|last6=Ravenna|first6=F}}
{{Adrenergics}}{{organic-compound-stub}}{{pharma-stub}}

6 : Beta blockers|Isopropyl compounds|Alcohols|Amines|Phenol ethers|Cyclohexanes

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