词条 | FMISO |
释义 |
| drug_name = [18F]Fluoromisonidazole | IUPAC_name = 1-(2-Nitro-imidazolyl)-3-[18F]fluoro-2-propanol | image = 18F-Fluoromisonidazole.svg | alt = | caption = | tradename = | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_AU_comment = | legal_CA = | legal_NZ = | legal_UK = | legal_US = | legal_UN = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | metabolites = | onset = | elimination_half-life = | duration_of_action = | excretion = | CAS_number = | ATCvet = | ATC_prefix = | ATC_suffix = | PubChem = | DrugBank = | ChemSpiderID = 396524 | synonyms = [18F]FMISO; 1H-1-(3-[18F]fluoro-2-hydroxypropyl)-2-nitroimidazole | chemical_formula = C6H818FN3O | molecular_weight = 188.15 g/mol }}FMISO or fluoromisonidazole is used as a PET radiotracer for imaging hypoxia when labeled with fluorine-18.[1] References1. ^{{cite journal|last1=Rajendran|first1=JG|last2=Mankoff|first2=DA|last3=O'Sullivan|first3=F|last4=Peterson|first4=LM|last5=Schwartz|first5=DL|last6=Conrad|first6=EU|last7=Spence|first7=AM|last8=Muzi|first8=M|last9=Farwell|first9=DG|last10=Krohn|first10=KA|title=Hypoxia and glucose metabolism in malignant tumors: evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging.|journal=Clinical Cancer Research|date=1 April 2004|volume=10|issue=7|pages=2245–52|pmid=15073099|doi=10.1158/1078-0432.ccr-0688-3}} External links
2 : PET radiotracers|Nitroimidazoles |
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