词条 | Frank Dickens (biochemist) |
释义 |
Early lifeHe was born in Northampton, England, and educated at Northampton Grammar School. He father was the owner of a leather factory in Kettering Road, Northampton, which his four brothers joined and turned into Dickens Brothers Ltd. However, Frank developed an interest in science and won a scholarship to Magdalene College, Cambridge in 1918. He did not take this up till 1919 as he enlisted in the army, becoming a second lieutenant in the Northamptonshire Regiment, although he was not in action. He graduated in 1921, with a 2nd class degree, and then attended Imperial College, London and obtained a PhD in organic chemistry.[1] CareerIn 1923 he began research at the Middlesex Hospital in London working with Dodds on insulin to make it available for patients. He then did work with Dodds on the isolation of the female sex hormone stilboestrol which led to its eventual synthesis in 1938.[2][3] He spent 1929 working with Otto Warburg in Berlin and later translated Warburg's book Über den Stoffwechsel der Tumoren (On the Metabolism of Tumours) into English.[1] From 1933 to 1946 Dickens was director of the Cancer Research Laboratory at the Royal Victoria Infirmary in Newcastle upon Tyne. Dodds then invited him back to the Courtauld Institute as the Philip Hill Professor of Experimental Biochemistry[4] where he did research on the mechanism of how energy is derived by living tissues from carbohydrates, known as the "pentose phosphate pathway", and its link to the rate of tumour growth.[1] Personal lifeHe married Molly Jelleyman of Northampton in 1925 and they had two daughters. He became a Fellow of the Royal Society in 1946. He died at Ferring, a small village now part of Worthing, West Sussex.[1] Bibliography
References1. ^1 2 3 4 Peter N. Campbell: Dickens, Frank (1899–1986), rev. Oxford Dictionary of National Biography, Oxford University Press, 2004, accessed 19 Nov 2012 {{authority control}}{{DEFAULTSORT:Dickens, Frank}}2. ^{{cite journal |vauthors=Dodds EC, Goldberg L, Lawson W, Robinson R | year =1938 | title = Estrogenic activity of certain synthetic compounds | journal = Nature | volume = 141 | issue = 3562 | pages = 247–8 | doi = 10.1038/141247b0 }} 3. ^British Medical Bulletin 1953: Vol 9 No 2 pp 105-109: Alternative Routes of Carbohydrate Chemistry Frank Dickens, accessed 20 November 2012 4. ^{{cite journal|title=Philip Hill Chair of Biochemistry: Dr. Frank Dickens, F.R.S |author=|date=26 October 1946|volume=158|issue=4017|doi=10.1038/158577b0|journal=Nature|page=577}} 7 : Alumni of Magdalene College, Cambridge|Fellows of the Royal Society|1899 births|1986 deaths|Alumni of Imperial College London|English biochemists|Physicians of the Middlesex Hospital |
随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。