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词条 GABA transporter type 3
释义

  1. See also

  2. References

GABA transporter type 3 (GAT3) uses sodium (Na+) electrochemical gradients to mediate uptake of GABA from the synaptic cleft by surrounding glial cells.[1]

Subtype-selective GAT3 inhibitors are known since 2015.[2]

See also

  • GABA transporter 1
  • GABA transporter 2
  • Solute carrier family

References

1. ^{{cite book|vauthors=Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ|title=Principles of Neural Science|edition=Fifth|date=2013|publisher=McGraw-Hill Companies|isbn=978-0-07-139011-8|page=296}}
2. ^{{cite journal |vauthors=Damgaard M, Al-Khawaja A, Vogensen SB, Jurik A, Sijm M, Lie ME, Bæk MI, Rosenthal E, Jensen AA, Ecker GF, Frølund B, Wellendorph P, Clausen RP |title=Identification of the First Highly Subtype-Selective Inhibitor of Human GABA Transporter GAT3 |journal=ACS Chem Neurosci |volume=6 |issue=9 |pages=1591–9 |year=2015 |pmid=26154082 |doi=10.1021/acschemneuro.5b00150 |url=}}
{{GABA metabolism and transport modulators}}{{membrane-protein-stub}}

3 : Solute carrier family|Neurotransmitter transporters|GABA

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