| 词条 | Gamma-Hydroxybutyraldehyde |
| 释义 |
| Name = γ-Hydroxybutyraldehyde | ImageFile = 4-Hydroxybutanal.svg | ImageSize = 200px | IUPACName = 4-Hydroxybutanal | OtherNames = |Section1={{Chembox Identifiers | CASNo = 25714-71-0 | PubChem = 93093 | ChemSpiderID = 84042 | SMILES = C(CC=O)CO | InChI = 1/C4H8O2/c5-3-1-2-4-6/h3,6H,1-2,4H2 | InChIKey = PIAOXUVIBAKVSP-UHFFFAOYAV | StdInChI = 1S/C4H8O2/c5-3-1-2-4-6/h3,6H,1-2,4H2 | StdInChIKey = PIAOXUVIBAKVSP-UHFFFAOYSA-N |Section2={{Chembox Properties | C=4 | H=8 | O=2 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} γ-Hydroxybutyraldehyde, also referred to as GHBAL, γ-hydroxybutaldehyde or γ-hydroxybutanal, is a chemical intermediate in the biosynthesis of the neurotransmitter γ-hydroxybutyric acid (GHB) from 1,4-butanediol (1,4-BD).[1] Like 1,4-BD, it also behaves as a prodrug to GHB when taken exogenously. However, as with all aliphatic aldehydes, γ-hydroxybutaldehyde is caustic and is strong-smelling and foul-tasting; thus, actual ingestion of this compound is likely to be unpleasant and result in severe nausea and vomiting. Metabolic pathway{{clear}}See also
References1. ^{{cite book|author1=Thomas L. Lemke|author2=David A. Williams|title=Foye's Principles of Medicinal Chemistry|url=https://books.google.com/books?id=Sd6ot9ul-bUC&pg=PA413|date=24 January 2012|publisher=Lippincott Williams & Wilkins|isbn=978-1-60913-345-0|pages=413–}} {{Neurotransmitter metabolism intermediates}}{{GHBergics}}{{GABAergics}}{{DEFAULTSORT:Hydroxybutyraldehyde, gamma-}}{{biochemistry-stub}} 5 : Aldehydes|GHB receptor agonists|GABAB receptor agonists|Prodrugs|Sedatives |
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