| 词条 | Gangliocytic paraganglioma |
| 释义 |
| name = Gangliocytic paraganglioma | synonyms = | image = Gangliocytic_paraganglioma_-_2_-_high_mag.jpg | caption = Micrograph of a gangliocytic paraganglioma. H&E stain. | pronounce = GP | field = Pathology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} A gangliocytic paraganglioma is a rare tumour that is typically found in the duodenum and consists of three components: (1) ganglion cells, (2) epithelioid cells (paraganglioma-like) and, (3) spindle cells (schwannoma-like).[1] SymptomsThe most common presentation is gastrointestinal bleed (~45% of cases), followed by abdominal pain (~43% of cases) and anemia (~15% of cases).[2] PathologyGP consist of three components (1) ganglion cells, (2) epithelioid cells (neuroendocrine-like), and (3) spindle cells (schwannoma-like). The microscopic differential diagnosis includes poorly differentiated carcinoma, neuroendocrine tumour and paraganglioma.[1] GPs may be sporadic or arise in the context neurofibromatosis type 1. See also
References1. ^1 {{Cite journal | last1 = Wong | first1 = A. | last2 = Miller | first2 = AR. | last3 = Metter | first3 = J. | last4 = Thomas | first4 = CR. | title = Locally advanced duodenal gangliocytic paraganglioma treated with adjuvant radiation therapy: case report and review of the literature | journal = World J Surg Oncol | volume = 3 | issue = 1 | pages = 15 |date=Mar 2005 | doi = 10.1186/1477-7819-3-15 | pmid = 15740625 | pmc=554089}} 2. ^{{Cite journal | last1 = Okubo | first1 = Y. | last2 = Wakayama | first2 = M. | last3 = Nemoto | first3 = T. | last4 = Kitahara | first4 = K. | last5 = Nakayama | first5 = H. | last6 = Shibuya | first6 = K. | last7 = Yokose | first7 = T. | last8 = Yamada | first8 = M. | last9 = Shimodaira | first9 = K. | last10 = Sasai | first10 = Daisuke | last11 = Ishiwatari | first11 = Takao | last12 = Tsuchiya | first12 = Masaru | last13 = Hiruta | first13 = Nobuyuki | title = Literature survey on epidemiology and pathology of gangliocytic paraganglioma | journal = BMC Cancer | volume = 11 | issue = | pages = 187 | month = | year = 2011 | doi = 10.1186/1471-2407-11-187 | pmid = 21599949 | pmc=3141762}} External links{{Medical resources| DiseasesDB = | ICD10 = | ICD9 = | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = }} 1 : Digestive system neoplasia |
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