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词条 Gisela Mosig
释义

  1. Early years

  2. Recognition

  3. Death

  4. Key publications

  5. References

{{Infobox scientist
|name = Gisela Mosig
|image =
|image_size =
|caption =
|birth_name =
|birth_date = {{birth date|1930|11|29|mf=yes}}
|birth_place = Saxony, Germany
|nationality = Germany
United States
|death_date = {{death date and age|2003|1|12|1930|11|29|mf=yes}}
|death_place = Nashville, Tennessee, U.S.
|field = Molecular genetics
|known_for = Molecular biology of enterobacteria phage T4
}}Gisela Mosig (November 29, 1930 – January 12, 2003) was a German-American molecular biologist best known for her work with enterobacteria phage T4.[1][2] She was among the first investigators to recognize the importance of recombination intermediates in establishing new DNA replication forks, a fundamental process in DNA replication.[1][1]

Early years

While growing up on a farm in Saxony, Mosig became interested in biology and physics.[2][3]

After World War II (when she was 14 years old), the region where she lived became part of East Germany and evolutionary teaching in her high school skewed toward Lysenkoism.[3] Finding the intellectual atmosphere intolerable, she fled to the west on her bicycle with only the belongings she could carry. After undergraduate studies at the University of Bonn, she earned her doctoral degree in plant genetics at the University of Cologne in 1959.[2]

From there, she was recruited to Vanderbilt University to study bacteriophage T4, a topic for which she became a leading investigator.[3] After postdoctoral research at Vanderbilt and then the Carnegie Institute of Washington at Cold Spring Harbor (with Nobel laureate A. D. Hershey), she returned to Vanderbilt as a faculty member in 1965, and became a citizen of the United States of America in 1968. Mosig served on the Vanderbilt faculty until her death in 2003.[3]

Recognition

  • Outstanding Graduate Teaching Award (Vanderbilt, 1989)[4]
  • Elected Fellow of the American Academy of Microbiology (1994)[3]
  • Earl Sutherland Prize for Achievement in Research (Vanderbilt, 1995)[5][2]

Death

Mosig died at Alive Hospice in Nashville a few years after being diagnosed with metastatic ovarian cancer. She was 72 years old.[3][2] In her will she endowed a fund to support scholarly travel for Vanderbilt graduate students in the biological sciences.[6]

Key publications

  • {{cite journal|last1=Mosig|first1=G|title=A map of distances along the DNA molecule of phage T4.|journal=Genetics|date=June 1968|volume=59|issue=2|pages=137–51|pmid=5702346|pmc=1211937}}
  • {{cite journal|last1=Luder|first1=A|last2=Mosig|first2=G|title=Two alternative mechanisms for initiation of DNA replication forks in bacteriophage T4: priming by RNA polymerase and by recombination.|journal=Proceedings of the National Academy of Sciences of the United States of America|date=February 1982|volume=79|issue=4|pages=1101–5|pmid=7041114|pmc=345908|doi=10.1073/pnas.79.4.1101}}
  • {{cite book|last1=Mathews|first1=Christoper K.|last2=Kutter|first2=Elizabeth M.|last3=Mosig|first3=Gisela|last4=Berget|first4=Peter B.|title=Bacteriophage T4|date=1983|publisher=American Soc. for Microbiology|location=Washington, D.C.|isbn=0914826565}}
  • {{cite journal|last1=Mosig|first1=G|title=The essential role of recombination in phage T4 growth|journal=Annual Review of Genetics|date=1987|volume=21|pages=347–71|doi=10.1146/annurev.ge.21.120187.002023|pmid=3327469}}
  • {{cite journal|last1=Mosig|first1=G|title=Recombination and recombination-dependent DNA replication in bacteriophage T4|journal=Annual Review of Genetics|date=1998|volume=32|pages=379–413|doi=10.1146/annurev.genet.32.1.379|pmid=9928485}}
  • {{cite journal|last1=Miller|first1=ES|last2=Kutter|first2=E|last3=Mosig|first3=G|last4=Arisaka|first4=F|last5=Kunisawa|first5=T|last6=Rüger|first6=W|title=Bacteriophage T4 genome|journal=Microbiology and Molecular Biology Reviews|date=March 2003|volume=67|issue=1|pages=86–156|pmid=12626685|pmc=150520|doi=10.1128/mmbr.67.1.86-156.2003}}

References

1. ^{{Cite journal|last=Syeda|first=Aisha H.|last2=Hawkins|first2=Michelle|last3=McGlynn|first3=Peter|date=2014-10-23|title=Recombination and replication|journal=Cold Spring Harbor Perspectives in Biology|volume=6|issue=11|pages=a016550|doi=10.1101/cshperspect.a016550|issn=1943-0264|pmc=4413237|pmid=25341919}}
2. ^{{cite web|title=Pioneering genetic researcher Gisela Mosig dies|date=January 24, 2003|url=http://www.mc.vanderbilt.edu/reporter/index.html?ID=2484|website=Vanderbilt Reporter|publisher=Vanderbilt University Medical Center|accessdate=January 16, 2017}}
3. ^{{cite journal|last1=Nossal|first1=NG|last2=Franklin|first2=JL|last3=Kutter|first3=E|last4=Drake|first4=JW|title=Gisela Mosig|journal=Genetics|date=November 2004|volume=168|issue=3|pages=1097–104|pmid=15579671|series=Anecdotal, historical and critical commentaries on genetics|pmc=1448779}}
4. ^{{cite web|title=Faculty and Graduate Student Awards|url=http://as.vanderbilt.edu/faculty/awards.php|website=Faculty and Graduate Student Awards|publisher=Vanderbilt University|accessdate=January 16, 2017}}
5. ^{{cite web|title=Earl Sutherland Prize for Achievement in Research|url=http://www.vanderbilt.edu/provost/faculty-highlights/earl-sutherland.php|website=www.vanderbilt.edu|publisher=lt University Office of the Provost|accessdate=January 17, 2017}}
6. ^Brasher, Joan. [https://news.vanderbilt.edu/archived-news/register/articles/index-id=6893.html Mosig bequest example of way to support research] Vanderbilt Register, October 10, 2003.
{{authority control}}{{DEFAULTSORT:Mosig, Gisela}}{{biologist-stub}}

16 : 1930 births|2003 deaths|People from Saxony|20th-century women scientists|Deaths from ovarian cancer|Deaths from cancer in Tennessee|Women molecular biologists|Molecular biologists|Phage workers|American molecular biologists|American geneticists|American virologists|German expatriates in the United States|German molecular biologists|German geneticists|German virologists

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