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词条 Glassy cell carcinoma of the cervix
释义

  1. Signs and symptoms

  2. Cause

  3. Diagnosis

  4. Treatment

  5. See also

  6. Additional images

  7. References

  8. Further reading

  9. External links

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| caption = Micrograph of a glassy cell carcinoma of the cervix. H&E stain.
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Glassy cell carcinoma of the cervix, also glassy cell carcinoma, is a rare aggressive malignant tumour of the uterine cervix.[1] The tumour gets its name from its microscopic appearance; its cytoplasm has a glass-like appearance.

Signs and symptoms

The signs and symptoms are similar to other cervical cancers and may include post-coital bleeding and/or pain during intercourse (dyspareunia). Early lesions may be completely asymptomatic.

Cause

{{Empty section|date=July 2017}}

Diagnosis

The diagnosis is based on tissue examination, e.g. biopsy.

Under the microscope, glassy cell carcinoma tumours are composed of cells with a glass-like cytoplasm, typically associated with an inflammatory infiltrate abundant in eosinophils and very mitotically active. PAS staining highlights the plasma membrane.[2]

Treatment

The treatment is dependent on the stage. Advanced tumours are treated with surgery (radical hysterectomy and bilateral salpingo-opherectomy), radiation therapy and chemotherapy.[2]

See also

  • Cervix
  • Cervical cancer
  • Villoglandular adenocarcinoma

Additional images

References

1. ^{{Cite journal | last1 = Nasu | first1 = K. | last2 = Takai | first2 = N. | last3 = Narahara | first3 = H. | title = Multimodal treatment for glassy cell carcinoma of the uterine cervix. | journal = J Obstet Gynaecol Res | volume = 35 | issue = 3 | pages = 584–7 |date=Jun 2009 | doi = 10.1111/j.1447-0756.2008.00968.x | PMID = 19527406 }}
2. ^{{Cite journal | last1 = Deshpande | first1 = AH. | last2 = Kotwal | first2 = MN. | last3 = Bobhate | first3 = SK. | title = Glassy cell carcinoma of the uterine cervix a rare histology. Report of three cases with a review of the literature. | journal = Indian J Cancer | volume = 41 | issue = 2 | pages = 92–5 | month = | year = | doi = | PMID = 15318016 | url = http://www.indianjcancer.com/text.asp?2004/41/2/92/12353}}

Further reading

  • {{cite journal|last1=Greer|first1=Benjamin E.|last2=Koh|first2=Wui-Jin|last3=Abu-Rustum|first3=Nadeem|last4=Bookman|first4=Michael A.|last5=Bristow|first5=Robert E.|last6=Campos|first6=Susana M.|last7=Cho|first7=Kathleen R.|last8=Copeland|first8=Larry|last9=Crispens|first9=Marta Ann|last10=Eifel|first10=Patricia J.|last11=Huh|first11=Warner K.|last12=Jaggernauth|first12=Wainwright|last13=Kapp|first13=Daniel S.|last14=Kavanagh|first14=John J.|last15=Lurain|first15=John R.|last16=Morgan|first16=Mark|last17=Morgan|first17=Robert J.|last18=Powell|first18=C. Bethan|last19=Remmenga|first19=Steven W.|last20=Reynolds|first20=R. Kevin|last21=Secord|first21=Angeles Alvarez|last22=Small|first22=William|last23=Teng|first23=Nelson|title=Uterine Neoplasms|journal=Journal of the National Comprehensive Cancer Network|date=1 May 2009|volume=7|issue=5|pages=498–531|doi=10.6004/jnccn.2009.0035|url=http://www.jnccn.org/content/7/5/498.long|accessdate=19 July 2017|language=en|issn=1540-1405}}

External links

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| ICD10 = C53.0 C53.1 C53.8
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| Orphanet = 213833
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  • Glassy cell carcinoma - micrograph (webpathology.com)
{{Genital neoplasia}}

3 : Gynaecological cancer|Rare diseases|Infectious causes of cancer

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