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词条 Gonadotropin-resistant ovary syndrome
释义

  1. References

{{Orphan|date=February 2013}}

Resistant ovary syndrome, previously known as Savage syndrome, is a cause of ovarian failure that can lead to secondary amenorrhea. Resistant ovaries result from a functional disturbance of the gonadotropin receptors in the ovarian follicles. It may be a cause of primary or secondary amenorrhea and is resistant to exogenous gonadotropin stimulation.

Diagnosis of this condition requires that the patient has a normal 46,XX karyotype, normal secondary sexual characteristics, elevated plasma follicle-stimulating hormone and luteinizing hormone – in the menopausal range – and that normal, multiple follicles are seen on ovarian biopsy.

Spontaneous reversal of the receptor resistance may occur.[1]

References

1. ^http://www.acfs2000.com/basic_services/premature-ovarian-failure-pof.html

1 : Menstrual disorders

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