Grumbach or von Grumbach is a surname. Notable people with the surname include:

• Antoine Grumbach, French architect
• Argula von Grumbach (1492–1554?), Bavarian noblewoman
• Detlef Grumbach (born 1955), German author and journalist
• Doris Grumbach (born 1918), American novelist, biographer, literary critic, and essayist
• Kevin Grumbach, American physician and academic
• Melvin M. Grumbach, American pediatrician and academic
• Wilhelm von Grumbach (1503–1567), German adventurer

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