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词条 Heme ligase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Heme ligase
| EC_number = 4.99.1.8
| CAS_number =
| IUBMB_EC_number = 4/99/1/8
| GO_code =
| image =
| width =
| caption =
}}Heme ligase ({{EC number|4.99.1.8}}, heme detoxification protein, HDP, hemozoin synthase) is an enzyme with systematic name Fe3+:ferriprotoporphyrin IX ligase (beta-hematin-forming).[1] This enzyme catalyses the following chemical reaction

2 ferriprotoporphyrin IX beta-hematin

This heme detoxifying enzyme is found in Plasmodium parasites.

References

1. ^{{cite journal | vauthors = Jani D, Nagarkatti R, Beatty W, Angel R, Slebodnick C, Andersen J, Kumar S, Rathore D | title = HDP-a novel heme detoxification protein from the malaria parasite | journal = PLoS Pathogens | volume = 4 | issue = 4 | pages = e1000053 | date = April 2008 | pmid = 18437218 | pmc = 2291572 | doi = 10.1371/journal.ppat.1000053 }}

External links

  • {{MeshName|Heme+ligase}}
{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 4.99.1

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