Hermes is a surname which may refer to:

• Ad Hermes (1929–2002), Dutch (CDA) politician
• Andreas Hermes (1878–1964), German politician, minister in several Weimar Republic governments and member of the anti-Nazi resistance
• Carli Hermès (born 1963), Dutch photographer and commercial director
• Georg Hermes (1775–1831), German Roman Catholic philosopher and theologian
• Gertrude Hermes (1901–1983), English wood engraver, printmaker and sculptor
• Hans Hermes (1912–2003), German mathematician
• Heriberto Hermes (1932-2018), American Roman Catholic bishop
• Johann Gustav Hermes (1846–1912), German mathematician
• Peter Hermes (1922-2015), West German Ambassador to the United States from 1979 to 1984, son of Andreas
• Will Hermes (born 1960), American author, broadcaster, journalist and critic

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