| 词条 | Herpes zoster ophthalmicus |
| 释义 |
| name = Ophthalmic zoster | image = Herpes zoster ophthalmicus.2.jpg | caption = Herpes zoster ophthalmicus | pronounce = | field = | synonyms = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }}Herpes zoster ophthalmicus (HZO) and also known as ophthalmic zoster is a disease characterised by reactivation of dormant varicella zoster virus residing within the ophthalmic nerve (the first division of the trigeminal nerve).[1]{{rp|380}}[2] This condition is an important subtype of shingles, representing 15% of all cases.[3] Herpes zoster ophthalmicus is transmitted via direct contact or droplets. Varicella zoster virus is a DNA virus which produces acidophilic intranuclear inclusion bodies. The virus is neurotrophic in nature. The frontal nerve is more commonly affected than the nasociliary nerve or lacrimal nerve.[4] Signs and symptomsSkin
Cornea{{See also|Cornea#Layers}}
UvealAnterior uveitis develops in 40–50% of cases with HZO within 2 weeks of onset of the skin rashes. Typical HZO keratitis at least mild iritis, especially if Hutchinson's sign is positive for the presence of vescicles upon the tip of the nose. Features:[4] This non-granulomatous iridocyclitis is associated with:
HZO uveitis is associated with complications such as iris atrophy and secondary glaucoma are not uncommon. Complicated cataract may develop in the late stages of the disease. TreatmentTreatment is usually with antivirals such as acyclovir by mouth. Uveal
References1. ^{{cite book |author=James, William D. |author2=Berger, Timothy G.|title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=|display-authors=etal}} 2. ^{{cite book |author=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages= |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}} 3. ^1 2 {{cite web|url=https://books.google.com/books/about/Oxford_Handbook_of_Ophthalmology.html?id=oFAFYRyFbr4C&redir_esc=y|title=Oxford Handbook of Ophthalmology|work=google.com.au}} 4. ^1 2 {{cite web|url=https://books.google.com/books/about/Comprehensive_Ophthalmology.html?id=0fSyGAAACAAJ&redir_esc=y|title=Comprehensive Ophthalmology|work=google.com.au}} External links{{Medical resources| ICD10 = {{ICD10|B|02||b|00}} | ICD9 = {{ICD9|053.20}} | ICDO = | OMIM = | MedlinePlus = 000858 | eMedicineSubj = med | eMedicineTopic = 1007 | eMedicine_mult = {{eMedicine2|derm|180}} {{eMedicine2|emerg|823}} {{eMedicine2|oph|257}} {{eMedicine2|ped|996}} | DiseasesDB = 29119 }} 2 : Varicella zoster virus-associated diseases|Ophthalmology |
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