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词条 Histolysain
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Histolysain
| EC_number = 3.4.22.35
| CAS_number = 92228-52-9
| IUBMB_EC_number = 3/4/22/35
| GO_code =
| image =
| width =
| caption =
}}Histolysain ({{EC number|3.4.22.35}}, histolysin, Entamoeba histolytica cysteine proteinase, amebapain, Entamoeba histolytica cysteine protease, Entamoeba histolytica neutral thiol proteinase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins, including basement membrane collagen and azocasein. Preferential cleavage: Arg-Arg- in small molecule substrates including Z-Arg-Arg-!NHMec

This enzyme is present in the protozoan, Entamoeba histolytica.

References

1. ^{{cite journal | vauthors = Lushbaugh WB, Hofbauer AF, Pittman FE | title = Entamoeba histolytica: purification of cathepsin B | journal = Experimental Parasitology | volume = 59 | issue = 3 | pages = 328–36 | date = June 1985 | pmid = 2860002 | doi = 10.1016/0014-4894(85)90088-8 }}
2. ^{{cite journal | vauthors = Luaces AL, Barrett AJ | title = Affinity purification and biochemical characterization of histolysin, the major cysteine proteinase of Entamoeba histolytica | journal = The Biochemical Journal | volume = 250 | issue = 3 | pages = 903–9 | date = March 1988 | pmid = 2898937 | pmc = 1148941 | doi = 10.1042/bj2500903 }}

External links

  • {{MeshName|Histolysain}}
{{Cysteine proteases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 3.4.22

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