| 词条 | HolA |
| 释义 |
| Name = DNA polymerase III, delta subunit | image = | width = | caption = | Organism = Escherichia coli (str. K-12 substr. MG1655) | TaxID = 511145 | Symbol = holA | AltSymbols = | EntrezGene = 947573 | PDB = | RefSeqmRNA = | RefSeqProtein = NP_415173.1 | UniProt = P28630 | ECnumber = 2.7.7.7 | Chromosome = genome | EntrezChromosome = NC_000913.2 | GenLoc_start = 669641 | GenLoc_end = 670982 }}{{Infobox protein family | Symbol = DNA_pol3_delta | Name = DNA polymerase III, delta subunit | image = PDB 1xxh EBI.jpg | width = | caption = atpgs bound e. coli clamp loader complex | Pfam = PF06144 | Pfam_clan = CL0023 | InterPro = IPR010372 | SMART = | PROSITE = | MEROPS = | SCOP = 1jql | TCDB = | OPM family = | OPM protein = | CAZy = | CDD = }} In molecular biology, holA is a gene that encodes the δ (delta) subunit of DNA polymerase III in E. coli and other bacteria. Along with the γ, δ', χ, and ψ subunits that make up the core polymerase, and the β accessory proteins, the δ subunit is responsible for the high speed and processivity of polIII.[1][2] References1. ^{{cite journal | vauthors = Dong Z, Onrust R, Skangalis M, O'Donnell M | title = DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta' | journal = The Journal of Biological Chemistry | volume = 268 | issue = 16 | pages = 11758–65 | date = June 1993 | pmid = 8505303 | url = http://www.jbc.org/content/268/16/11758.full.pdf }} {{molecular-biology-stub}}{{DNA replication}}2. ^{{cite journal | vauthors = Carter JR, Franden MA, Aebersold R, McHenry CS | title = Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme | journal = Journal of Bacteriology | volume = 174 | issue = 21 | pages = 7013–25 | year = 1992 | pmid = 1400251 | pmc = 207382 | url = http://jb.asm.org/content/174/21/7013.full.pdf }} 2 : Bacterial proteins|DNA replication |
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