| 词条 | Hydrangenol |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 442971440 | Name = Hydrangenol | ImageFile = Hydrangenol.svg | ImageSize = 200px | ImageName = Chemical structure of hydrangenol | ImageAlt = Chemical structure of hydrangenol | IUPACName = 8-hydroxy-3-(4-hydroxyphenyl)-3,4-dihydroisochromen-1-one | OtherNames = |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo = 480-47-7 | CASNoOther = | PubChem = 119199 | SMILES = C1C(OC(=O)C2=C1C=CC=C2O)C3=CC=C(C=C3)O | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 106486 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 5776 | InChI = 1/C15H12O4/c16-11-6-4-9(5-7-11)13-8-10-2-1-3-12(17)14(10)15(18)19-13/h1-7,13,16-17H,8H2 | InChIKey = DGKDFNDHPXVXHW-UHFFFAOYAS | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C15H12O4/c16-11-6-4-9(5-7-11)13-8-10-2-1-3-12(17)14(10)15(18)19-13/h1-7,13,16-17H,8H2 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = DGKDFNDHPXVXHW-UHFFFAOYSA-N | MeSHName = }} |Section2={{Chembox Properties | Formula = C15H12O4 | MolarMass = 256.25 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = | RPhrases = | SPhrases = }} }} Hydrangenol is a dihydroisocoumarin. It can be found in Hydrangea macrophylla, as well as its 8-O-glucoside.[1] (-)-hydrangenol 4'-O-glucoside[2] and (+)-hydrangenol 4'-O-glucoside[3] can be found in Hydrangeae Dulcis Folium, the processed leaves of H. macrophylla var. thunbergii. References1. ^{{Cite journal|title=Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and Thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats|journal= Biological & Pharmaceutical Bulletin|year= 1999|volume=22|issue=8|pages= 870–872|id={{INIST|1959604}}|doi=10.1248/bpb.22.870|last1=Matsuda|first1=Hisashi|last2=Simoda|first2=Hiroshi|last3=Yamahara|first3=Johji|last4=Yoshikawa|first4=Masayuki|pmid=10480329}} {{Isocoumarin}}{{Natural-phenol-stub}}2. ^{{Cite journal|pmid=1363465|year=1992|last1=Yoshikawa|first1=M|last2=Uchida|first2=E|last3=Chatani|first3=N|last4=Kobayashi|first4=H|last5=Naitoh|first5=Y|last6=Okuno|first6=Y|last7=Matsuda|first7=H|last8=Yamahara|first8=J|last9=Murakami|first9=N|title=Thunberginols C, D, and E, new antiallergic and antimicrobial dihydroisocoumarins, and thunberginol G 3'-O-glucoside and (-)-hydrangenol 4'-O-glucoside, new dihydroisocoumarin glycosides, from Hydrangeae Dulcis Folium|volume=40|issue=12|pages=3352–4|journal=Chemical & Pharmaceutical Bulletin|doi=10.1248/cpb.40.3352}} 3. ^{{Cite journal|pmid=8795265|id= {{INIST|3226693}}|year=1996|last1=Yoshikawa|first1=M|last2=Matsuda|first2=H|last3=Shimoda|first3=H|last4=Shimada|first4=H|last5=Harada|first5=E|last6=Naitoh|first6=Y|last7=Miki|first7=A|last8=Yamahara|first8=J|last9=Murakami|first9=N|title=Development of bioactive functions in hydrangeae dulcis folium. V. On the antiallergic and antimicrobial principles of hydrangeae dulcis folium. (2). Thunberginols C, D, and E, thunberginol G 3'-O-glucoside, (-)-hydrangenol 4'-o-glucoside, and (+)-hydrangenol 4'-O-glucoside|volume=44|issue=8|pages=1440–7|journal=Chemical & Pharmaceutical Bulletin|doi=10.1248/cpb.44.1440 }} 1 : Dihydroisocoumarins |
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