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词条 Hydromadinone acetate
释义

  1. See also

  2. References

{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = [(6S,8R,9S,10R,13S,14S,17R)-17-Acetyl-6-chloro-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
| image = Hydromadinone acetate.svg
| width = 250px
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| class = Progestogen; Progestogen ester
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref =
| CAS_number = 2477-73-8
| CAS_supplemental =
| ATC_prefix =
| ATC_suffix =
| ATC_supplemental =
| PubChem = 200665
| IUPHAR_ligand =
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID = 173710
| UNII = X8WV0125VZ
| KEGG =
| ChEBI =
| ChEMBL =
| synonyms = NSC-33170; Chloroacetoxyprogesterone; CAP; 6α-Chloro-17α-acetoxyprogesterone; 6α-Chloro-17α-acetoxypregn-4-ene-3,20-dione
| C=23 | H=31 | Cl=1 | O=4
| SMILES = CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@@H](C4=CC(=O)CC[C@]34C)Cl)C)OC(=O)C
| StdInChI_Ref =
| StdInChI = 1S/C23H31ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h11,16-18,20H,5-10,12H2,1-4H3/t16-,17+,18+,20+,21-,22+,23+/m1/s1
| StdInChIKey_Ref =
| StdInChIKey = DCVGANSDLNPXGO-WXLIAARGSA-N
}}Hydromadinone acetate (developmental code name NSC-33170), also known as chloroacetoxyprogesterone (CAP), as well as 6α-chloro-17α-acetoxyprogesterone or 6α-chloro-17α-acetoxypregn-4-ene-3,20-dione, is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed.[1][2] It is the C17α acetate ester of hydromadinone, which, similarly, was never marketed.[1]

See also

  • List of progestogens
  • List of progestogen esters

References

1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA255|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=255–}}
2. ^{{cite book|author1=Martin Negwer|author2=Hans-Georg Scharnow|title=Organic-chemical drugs and their synonyms: (an international survey)|url=https://books.google.com/books?id=1nBqAAAAMAAJ|year=2001|publisher=Wiley-VCH|isbn=978-3-527-30247-5|page=3723}}
{{Progesterone receptor modulators}}{{Steroid-stub}}{{Genito-urinary-drug-stub}}

7 : Abandoned drugs|Acetate esters|Diketones|Organochlorides|Pregnanes|Progestogen esters|Progestogens

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