Hyperacanthus may refer to:

• Hyperacanthus (mollusc)
• Hyperacanthus (plant), a genus in the family Rubiaceae

• Perfluorotriamylamine
• Perfluorotributylamine
• Perfluortributylamine
• Perflutren
• PerFoam
• Perfoliate bellwort
• Perfoliate pondweed
• Perforadix
• Perforadix sacchari
• Perforate Acetabulum
• Perforated acetabulum
• Perforated baton
• Perforated hose
• Perforated intestine
• Perforated paper tape
• Perforated-scale sardine
• Perforation (disambiguation)
• Perforation gauge
• Perforator flaps
• Perforator vein
• Perforce
• Perforene
• PERFORM-3D
• Performa 250
• Performa 400