| 词条 | Ian Calman Muir MacLennan |
| 释义 |
|name = Ian Calman Muir MacLennan |image = |birth_date = {{Birth date and age|1939|12|30|df=y}} |birth_place = |death_date = |death_place = |nationality = |field = Immunology |alma_mater = |work_institution = University of Birmingham |doctoral_advisor = |doctoral_students= |known_for = contributions to immunology discovered marginal zone B-cells |prizes = FRS (2012) |religion = |footnotes = }} Ian Calman Muir MacLennan is Emeritus Professor of Immunology at the University of Birmingham MRC Centre for Immune Regulation in Birmingham, UK. He was born on 30 December 1939.[1] He has made pioneering contributions to immunology and was the first to discover marginal zone B-cells. He was made a Commander of the Order of the British Empire in the Queen's Birthday Honours in 2005.[2] He was elected a Fellow of the Royal Society (FRS) in 2012, his nomination reads:{{centered pull quote|Ian MacLennan has made several landmark contributions to immunology and especially our understanding of antibody production. His classic experiments led him propose a role for germinal centres in affinity maturation of antibody responses by a process of hypermutation followed by antigen-mediated selection. Subsequently, he identified the basis of the multi-step selection process that protects against autoantibody production. He also first discovered marginal zone B cells and identified how they counter encapsulated bacterial infection. His early work revealed and characterized the cells now termed NK cells and their capacity to kill antibody-coated nucleated cells.}}[3] References1. ^{{cite book|first1=|editor1-last=Bott|editor1-first=Simon|title=Who's Who of British Scientists 1980/81|date=1980|publisher=Simon Books Limited|isbn=9780862290016|page=317|edition=3rd}} {{FRS 2012}}{{Authority control}}{{DEFAULTSORT:MacLennan, Ian Calman Muir}}{{UK-scientist-stub}}2. ^{{Citation|title=Queen's Birthday Honours List|magazine=The Times Higher Education|date=17 June 2005|url=http://www.timeshighereducation.co.uk/news/queens-birthday-honours-list/196741.article|accessdate=4 May 2015}} 3. ^{{cite web|title=Professor Ian Calman Muir MacLennan CBE FMedSci FRS|url=https://royalsociety.org/people/fellowship/2012/ian-maclennan/|publisher=The Royal Society|accessdate=4 May 2015}} 5 : British immunologists|Fellows of the Royal Society|Living people|Academics of the University of Birmingham|1939 births |
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