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词条 Infectious pancreatic necrosis birnavirus Vp4 peptidase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Infectious pancreatic necrosis birnavirus Vp4 peptidase
| EC_number = 3.4.21.115
| CAS_number =
| IUBMB_EC_number = 3/4/21/115
| GO_code =
| image =
| width =
| caption =
}}Infectious pancreatic necrosis birnavirus Vp4 peptidase ({{EC number|3.4.21.115}}, infectious pancreatic necrosis virus protease, IPNV Vp4 protease, IPNV Vp4 peptidase, NS protease, NS-associated protease, Vp4 protease) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Cleaves the (Ser/Thr)-Xaa-Ala-(Ser/Ala)-Gly motif in the polyprotein NH2-pVP2-VP4-VP3-COOH of infectious pancreatic necrosis virus at the pVP2-VP4 and VP4-VP3 junctions

Infectious pancreatic necrosis virus is a birnavirus that causes an acute, contagious disease in young salmonid fish.

References

1. ^{{cite journal | vauthors = Manning DS, Leong JC | title = Expression in Escherichia coli of the large genomic segment of infectious pancreatic necrosis virus | journal = Virology | volume = 179 | issue = 1 | pages = 16–25 | date = November 1990 | pmid = 2219718 | doi = 10.1016/0042-6822(90)90268-v }}
2. ^{{cite journal | vauthors = Petit S, Lejal N, Huet JC, Delmas B | title = Active residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virus | journal = Journal of Virology | volume = 74 | issue = 5 | pages = 2057–66 | date = March 2000 | pmid = 10666235 | pmc = 111686 | doi = 10.1128/jvi.74.5.2057-2066.2000 }}
3. ^{{cite journal | title = The molecular biology of infectious pancreatic necrosis virus (IPNV) |author = Dobos, P. |journal = Annu. Rev. Fish Dis. |year = 1995 |volume = 5 |pages = 25–54 |pmid = |doi=10.1016/0959-8030(95)00003-8}}

External links

  • {{MeshName|Infectious+pancreatic+necrosis+birnavirus+Vp4+peptidase}}
{{Serine endopeptidases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 3.4.21

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