RUC may refer to:

• {{lang|pt|Rádio Universidade de Coimbra}} or Coimbra University Radio, a Portuguese university station
• Rapid Update Cycle, an atmospheric prediction system
• Renmin University of China, Beijing
• Road User Charges (RUC), taxes payable in New Zealand
• Roskilde University or Roskilde Universitetscenter
• Royal Ulster Constabulary, the police force in Northern Ireland from 1922 to 2001
• Specialty Society Relative Value Scale Update Committee, for US healthcare pricing

Ruc may refer to:

• Chut language in Vietnam, also known as Ruc or Ruc-Sach
• Rục people

• The Immortal (1970)
• The Immortal (2000)
• The Immortal Alamo
• The Immortal Bachelor
• The Immortal Battalion
• The Immortal (computer game)
• The Immortal Garrison
• The Immortal Heart
• The Immortal Hour (play)
• The Immortal (Invincible)
• The Immortality of Writers
• The Immortal Lee County Killers
• The Immortal Legions
• The Immortal Life of Henrietta Lacks
• The Immortal Man
• The immortal one
• The Immortals (disambiguation)
• The Immortals (film)
• The Immortals (NCIS episode)
• The Immortals (novel series)
• The Immortals of Meluha
• The Immortals Of Meluha
• The Immortals series
• The Immortals (Stewart and Riddell novel)
• The Immortal Storm