Jean Dubois may refer to:

• Jean Dubois (canoeist) (born 1914), Belgian sprint canoeist
• Jean Dubois (field hockey) (born 1926), Belgian field hockey player
• Jean Dubois the Elder (1604–1679), French landscape painter
• Jean Dubois (bishop) (1764–1842), French Catholic missionary in Virginia and Appalachians, third bishop of New York
• Jean-Antoine Dubois (1765–1848), French Catholic missionary in India
• Jean Dubois (linguist) (1920–2005), French linguist

• Department of Energy (United States)
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• Department of Environment, Land, Water & Planning
• Department of Environment (United Kingdom)
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• Department of External Affairs (1901-16)
• Department of External Affairs (1921-70)
• Department of External Territories
• Department of External Territories (1941-51)
• Department of External Territories (1968-73)
• Department of Extra-Normal Operations
• Department of Families (Manitoba)
• Department of Family and Community Services and Justice
• Department of Field Support
• Department of Films and Publications
• Department of Films & Publications
• Department of Finance (1976-97)