John Combe may refer to:

• John Combe (MP)
• John Frederick Boyce Combe, British Army officer
• John Combe (mayor), List of mayors of St. Joseph, Missouri

• Selection pressure
• Selection process
• Selection (relational algebra)
• Selection rules (physics)
• Selections For Friends
• Selections from Irving Berlin's White Christmas
• Selections from the Arista Years
• Selections From the Arista Years
• Selections from the Writings of the Báb
• Selection Sixteen
• Selection task
• Selective abortion
• Selective abortion and infanticide
• Selective abortion and infanticide of females
• Selective absorber
• Selective ACK
• Selective acknowledgement
• Selective adsorption
• Selective agonist
• Selective amnesia
• Selective and non-selective
• Selective androgen receptor modulator
• Selective androgen receptor modulators
• Selective area metering
• Selective assassination