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词条 Joomyeong Kim
释义

  1. Education

  2. Selected publications

  3. References

  4. External links

{{Infobox scientist
| name = Joomyeong Kim
| image = File:Joomyeong Kim.jpg
| caption = Professor Joomyeong Kim
| birth_name = Joomyeong Kim
| birth_date =
| birth_place =
| residence = Baton Rouge, Louisiana
| nationality = American / South Korean
| death_date =
| death_place =
| education = LSU Medical Center at New Orleans, LA (Ph. D.)
Seoul National University (M.S., B.S.)
| alma_mater = LSU Medical Center at New Orleans, LA (Ph. D., 1995)
| field = Genomic imprinting; Epigenetics
| work_institutions = Oak Ridge National Laboratory
Lawrence Livermore National Laboratory
Louisiana State University
| doctoral_advisor =
| known_for =
| prizes =
| spouse =
}}Joomyeong Kim is a Russell Thompson, Jr. Family Professor of Biology at Louisiana State University. His research interests include genomic imprinting and epigenetics. Dr. Kim's laboratory is mainly involved in understanding the functions and regulatory mechanisms governing genes subject to genomic imprinting.[1] Having previously characterized an imprinted domain located on proximal mouse chromosome 7/ human chromosome 19q13.4, his laboratory currently focuses on understanding regulatory mechanisms directing the mono-allelic expression of the seven imprinted genes in the cluster: Peg3, Usp29, Zfp264, APeg3 (paternally expressed) and Zim1, Zim2, Zim3 (maternally expressed).[2][3][4][5][6][7][8] As a second project direction, his lab studies the function of the dominant gene in the cluster, Peg3, as a transcriptional regulator.[9][10][11][12] Past projects in the Kim lab have included studying the epigenetic instability of imprinted genes during tumorigenesis,[13][14][15] potential roles of AEBP2 as a PRC2 targeting protein and in neural crest cell development,[16][17][18] as well as the DNA methylation of mouse and human retrotransposons.[19][20]

Education

  • Ph.D. Biochemistry and Molecular Biology, LSU Medical Center at New Orleans, LA (Advisor, Dr. Prescott L. Deininger)
  • M.S. Microbiology, Seoul National University, Seoul, South Korea (Advisor, Dr. John Jeongbin Yim) (1988)
  • B.S. Microbiology, Seoul National University, Seoul, South Korea (1986)

Selected publications

  • {{cite journal | pmid = 22394678 | doi=10.1093/hmg/dds092 | pmc=3363340 | volume=21 | title=Imprinting control region (ICR) of the Peg3 domain | year=2012 | author=Kim J, Ekram MB, Kim H, Faisal M, Frey WD, Huang JM, Tran K, Kim MM, Yu S | journal=Hum Mol Genet | pages=2677–87}}
  • {{cite journal | pmid = 24040411 | doi=10.1371/journal.pone.0075417 | pmc=3769284 | volume=8 | title=Identification of an evolutionarily conserved cis-regulatory element controlling the Peg3 imprinted domain | year=2013 | author=Thiaville MM, Kim H, Frey WD, Kim J | journal=PLoS One | page=e75417}}
  • {{cite journal | pmid = 24391757 | doi=10.1371/journal.pone.0083359 | volume=8 | title=Peg3 mutational effects on reproduction and placenta-specific gene families | pmc=3877027 | year=2013 | author=Kim J, Frey WD, He H, Kim H, Ekram MB, Bakshi A, Faisal M, Perera BP, Ye A, Teruyama R | journal=PLoS One | page=e83359}}
  • {{cite journal | pmid = 23078764 | doi=10.1016/j.gene.2012.10.005 | volume=512 | title=DNA-binding motif and target genes of the imprinted transcription factor PEG3 | pmc=3513644 | date=January 2013 | author=Thiaville MM, Huang JM, Kim H, Ekram MB, Roh TY, Kim J | journal=Gene | pages=314–20}}

References

1. ^{{cite web|url=https://sites01.lsu.edu/faculty/jkim/interests/| title=Joomyeong Kim|accessdate = Nov 15, 2017}}
2. ^{{cite journal |vauthors=Kim J, Ekram MB, Kim H, Faisal M, Frey WD, Huang JM, Tran K, Kim MM, Yu S | title = Imprinting control region (ICR) of the Peg3 domain | journal = Hum Mol Genet | volume = 21 | issue = 12 | pages = 2677–87 |date=2012 | pmid = 22394678 | pmc = 3363340 | doi=10.1093/hmg/dds092}}
3. ^{{cite journal |vauthors=Thiaville MM, Kim H, Frey WD, Kim J | title = Identification of an evolutionarily conserved cis-regulatory element controlling the Peg3 imprinted domain | journal = PLOS ONE | volume = 8 | issue = 9 | pages = e75417 |date=2013 | pmid = 24040411 | pmc = 3769284 | doi=10.1371/journal.pone.0075417}}
4. ^{{cite journal |vauthors=Kim J, Ye A | title = Phylogenetic and Epigenetic Footprinting of the Putative Enhancers of the Peg3 Domain | journal = PLOS ONE | volume = 11 | issue = 4 | pages = e0154216 |date=2016 | pmid = 27104590 | pmc = 4841594 | doi=10.1371/journal.pone.0154216}}
5. ^{{cite journal |vauthors=Perera BP, Kim J | title = Alternative promoters of Peg3 with maternal specificity | journal = Sci Rep | volume = 6 | pages = 24438 |date=2016 | pmid = 27075691 | pmc = 4830991 | doi=10.1038/srep24438}}
6. ^{{cite journal |vauthors=He H, Perera BP, Ye A, Kim J | title = Parental and sexual conflicts over the Peg3 imprinted domain | journal = Sci Rep | volume = 6 | pages = 38136 |date=2016 | pmid = 27901122 | pmc = 128876 | doi=10.1038/srep38136}}
7. ^{{cite journal |vauthors=He H, Ye A, Perera BP, Kim J | title = YY1's role in the Peg3 imprinted domain | journal = Sci Rep | volume = 7 | pages = 6427 |date=2017 | pmid = 28743993 | pmc = 5526879 | doi=10.1038/s41598-017-06817-5}}
8. ^{{cite journal |vauthors=Bretz CL, Kim J | title = Transcription-driven DNA methylation setting on the mouse Peg3 locus | journal = Epigenetics | volume = Sep 19 [Epub ahead of print] | pages = 1–8 |date=2017 | pmid = 28925797 | doi=10.1080/15592294.2017.1377869}}
9. ^{{cite journal |vauthors=Ye A, He H, Kim J| title = Paternally expressed Peg3 controls maternally expressed Zim1 as a trans factor | journal = PLOS ONE | volume = 9 | issue = 9 | pages = e108596 | date=2014 | pmid = 25265264 | pmc = 4180786 | doi=10.1371/journal.pone.0108596}}
10. ^{{cite journal |vauthors=Lee S, Ye A, Kim J | title = DNA-Binding Motif of the Imprinted Transcription Factor PEG3 | journal = PLOS ONE | volume = 10 | issue = 12 | pages = e0145531 | date=2015 | pmid = 26692216 | pmc = 4686966 | doi=10.1371/journal.pone.0145531}}
11. ^{{cite journal |vauthors=Ye A, He H, Kim J | title = PEG3 binds to H19-ICR as a transcriptional repressor | journal = Epigenetics | volume = 11 | issue = 12 | pages = 889–900 | date=2016 | pmid = 27824289 | pmc = 5193492 | doi=10.1080/15592294.2016.1255385}}
12. ^{{cite journal |vauthors=Ye A, He H, Kim J | title = PEG3 control on the mammalian MSL complex | journal = PLOS ONE | volume = 12 | issue = 6 | pages = e0178363 | date=2017 | pmid = 28609438 | pmc = 5469463 | doi=10.1371/journal.pone.0178363}}
13. ^{{cite journal |vauthors=Kim J, Bretz CL, Lee S| title = Epigenetic instability of imprinted genes in human cancers | journal = Nucleic Acids Res | volume = 43 | issue = 22 | pages = 10689–99 | date=2015 | pmid = 26338779 | pmc = 4678850 | doi=10.1093/nar/gkv867}}
14. ^{{cite journal |vauthors=Bretz CL, Langohr IM, Lee S, Kim J | title = Epigenetic instability at imprinting control regions in a Kras(G12D)-induced T-cell neoplasm | journal = Epigenetics | volume = 10 | issue = 12 | pages = 1111–201 | date=2015 | pmid = 26507119 | pmc = 4844204 | doi=10.1080/15592294.2015.1110672}}
15. ^{{cite journal |vauthors=Bretz CL, Langohr IM, Kim J | title = Epigenetic response of imprinted domains during carcinogenesis | journal = Clin Epigenetics | volume = 9 | pages = 90 | date=2017 | pmid = 28855972 | pmc = 5572065 | doi=10.1186/s13148-017-0393-8}}
16. ^{{cite journal |vauthors=Kim H, Kang K, Kim J| title = AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2 | journal = Nucleic Acids Res | volume = 37 | issue = 9 | pages = 2940–50 | date=2009 | pmid = 19293275| pmc = 2685092 | doi=10.1093/nar/gkp149}}
17. ^{{cite journal |vauthors=Kim H, Kang K, Ekram MB, Roh TY, Kim J | title = Aebp2 as an epigenetic regulator for neural crest cells | journal = PLOS ONE | volume = 6 | issue = 9 | pages = e25174 | date=2011 | pmid = 21949878 | pmc = 3176318 | doi=10.1371/journal.pone.0025174}}
18. ^{{cite journal |vauthors=Kim H, Ekram MB, Bakshi A, Kim J | title = AEBP2 as a transcriptional activator and its role in cell migration | journal = Genomics | volume = 105 | issue = 2 | pages = 108–15 | date=2015 | pmid = 25451679 | pmc = 4314425 | doi=10.1016/j.ygeno.2014.11.007}}
19. ^{{cite journal |vauthors=Bakshi A, Kim J| title = Retrotransposon-based profiling of mammalian epigenomes: DNA methylation of IAP LTRs in embryonic stem, somatic and cancer cells | journal = Genomics | volume = 104 | pages = 538–44 | date=2014 | pmid = 25277721| pmc = 4262695 | doi=10.1016/j.ygeno.2014.09.009}}
20. ^{{cite journal |vauthors=Bakshi A, Herke SW, Batzer MA, Kim J | title = ADNA methylation variation of human-specific Alu repeats | journal = Epigenetics | volume = 11 | issue = 2 | pages = 163–73 | date=2016 | pmid = 26890526 | pmc = 4846114 | doi=10.1080/15592294.2015.1130518}}
21. ^{{cite web|url=http://www.biology.lsu.edu/cos/biosci/FacultyandStaff/Faculty/item40761.html|title=Joomyeong Kim}}
22. ^{{cite journal |vauthors=Kim J, Ashworth L, Branscomb E, Stubbs L | title = The human homolog of a mouse-imprinted gene, PEG3, maps to a zinc finger gene-rich region of human chromosome 19q13.4 | journal = Genome Res | volume = 7 | issue = 5 | pages = 532–40 |date=August 1997 | pmid = 9149948 | pmc = 310658 | doi = 10.1101/gr.7.5.532}}
23. ^{{cite web | title = Entrez Gene: PEG3 paternally expressed 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5178| accessdate = }}
24. ^{{cite web|url=http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0083359|| volume = 8 | issue = 12 |author1=Kim J |author2=Frey Wesley D. |author3=He Hongzhi |author4=Ekram Muhammed B. |author5=Bakshi Arundhati |author6=Faisal Mohammed |author7=Perera Bambarendage P. U. |author8=Ye An |author9=Teruyama Ryoichi ||date=December 31, 2013|| accessdate = May 22, 2014|title=Peg3 Mutational Effects on Reproduction and Placenta-Specific Gene Families}}

External links