Joseph Bruno (born 1929) is an American businessman and Republican politician in New York.

Joseph Bruno may also refer to:

• Joseph F. Bruno (born 1944), public official in New York City
• Joseph James Bruno (c. 1878–1951), mastermind of the Kelayres massacre, prison escapee
• Joseph Bruno (Maine politician) (born 1955), American politician from Maine
• Joe Bruno (rugby league) (born 1985), Papua New Guinea rugby league international
• Joseph W. Bruno (born 1955), American academic and president of Marietta College
• J. Jon Bruno (Joseph Jon Bruno, born 1946), Episcopal bishop of Los Angeles

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