Karakuyu means "black well" in Turkic languages and may refer to:

• Karakuyu, Aksaray, village in Aksaray Province, Turkey
• Karakuyu, Dinar, village in Afyonkarahisar Province, Turkey
• Karakuyu, Emirdağ, village in Afyonkarahisar Province, Turkey
• Karakuyu, Karaisalı, village in Adana Province, Turkey
• Karakuyu, Korkuteli, village in Antalya Province, Turkey
• Karakuyu, Polatlı, village in Ankara Province, Turkey
• Karakuyu, Saimbeyli, village in Adana Province, Turkey
• Karakuyu, Seyhan, village in Adana Province, Turkey

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