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Ketchum is a surname that originated in England. Not all people in America who descended from the Ketchu(a)m come from the same man. An example of English descent is Edward Ketcham (Chetham as it was spelled in England on the records of his first marriage to Mary Hall and the birth of his first children). There are no known records of his parents, nor any siblings. Edward is not found on any passenger list, but he came to America during the Great Puritan Migration. He can be found with his family in Ipswich, Mass, in the 1630s. It is assumed Edward was born in about 1590, though no record of his birth has been located. As far as we currently know, there is NOT A CONNECTION between this Edward (Chetham) Ketcham/Ketchum who came to America and the Chetham family of Crumpsall, Lancashire, England from which Sir Humphrey Chetham (born 1580) is from, for whom the Chetham Library in Manchester England is named. Notable people with the surname include: - Annie Chambers Ketchum (1824-1904; (religious name, Sister Amabilis), American educator, lecturer, writer
- Brandon Ketchum (born 1976), speculative fiction writer
- Daniel Ketchum (born 1981), former American swimmer
- Gerald Ketchum (1908–1992), commanded the icebreaker USS Burton Island (AG-88)
- Gus Ketchum (1897–1980), American Major League Baseball pitcher
- Hal Ketchum (born 1953), country music singer
- Jack Ketchum (1946–2018), horror writer
- Jesse Ketchum (1782–1867), tanner and political figure in Upper Canada
- Menis E. Ketchum, Chief Justice of the Supreme Court of Appeals of West Virginia
- Morris Ketchum (1796–1880), American banker and financier of the 19th century
- Richard Ketchum (1773–1845), political figure in New Brunswick
- Robert Glenn Ketchum (born 1947), landscape and nature photographer
- Rufus Lloyd Ketchum, a Sergeant in the United States Army during the Korean War
- Tom Ketchum (1863–1901), a.k.a. "Black Jack" Ketchum, U.S. Western outlaw
- Wesley Harrington Ketchum (1878–1968), medical doctor, introduced Edgar Cayce to the national medical community in a 1910 presentation to the American Association for Clinical Research
- William Ketchum, 14th Mayor of the City of Buffalo, New York
- William F. Ketchum, inventor of the Ketchum Hand Grenade
- William M. Ketchum (1921–1978), U.S. Representative
- William Scott Ketchum (1813–1871), U. S. Army officer before and during the American Civil War
Fictional characters:- Ash Ketchum, a Pokémon Trainer
- Delia Ketchum, his mother
- Kevin Ketchum, an OZ prisoner
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