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词条 LARP6
释义

  1. Clinical relevance

  2. References

  3. Further reading

{{Infobox_gene}}La-related protein 6 also known as acheron or La ribonucleoprotein domain family member 6 (LARP6), is a protein that in humans is encoded by the LARP6 gene.[1]

Clinical relevance

In a recent genome-wide association study, LARP6 gene has been associated with fasting glucose traits, type 2 diabetes and obesity.[2]

References

1. ^{{cite web | title = Entrez Gene: La ribonucleoprotein domain family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55323| accessdate = }}
2. ^{{cite journal |vauthors=Strawbridge RJ, Dupuis J, Prokopenko I, etal | title = Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes | journal = Diabetes | volume = 60| issue = 10| pages = 2624–34|date=August 2011 | pmid = 21873549 | doi = 10.2337/db11-0415 | pmc=3178302}}

Further reading

{{refbegin | 2}}
  • {{cite journal |vauthors=Cai L, Fritz D, Stefanovic L, Stefanovic B |title=Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen. |journal=J. Mol. Biol. |volume=395 |issue= 2 |pages= 309–26 |year= 2010 |pmid= 19917293 |doi= 10.1016/j.jmb.2009.11.020 |pmc=2826804}}
  • {{cite journal |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
  • {{cite journal |vauthors=Glenn HL, Wang Z, Schwartz LM |title=Acheron, a Lupus antigen family member, regulates integrin expression, adhesion, and motility in differentiating myoblasts. |journal=Am. J. Physiol., Cell Physiol. |volume=298 |issue= 1 |pages= C46–55 |year= 2010 |pmid= 19889961 |doi= 10.1152/ajpcell.00387.2009 |pmc=2806151}}
  • {{cite journal |vauthors=Valavanis C, Wang Z, Sun D, etal |title=Acheron, a novel member of the Lupus Antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta |journal=Gene |volume=393 |issue= 1–2 |pages= 101–9 |year= 2007 |pmid= 17383118 |doi= 10.1016/j.gene.2007.01.033 |pmc=2739619}}
  • {{cite journal |vauthors=Barbe L, Lundberg E, Oksvold P, etal |title=Toward a confocal subcellular atlas of the human proteome. |journal=Mol. Cell. Proteomics |volume=7 |issue= 3 |pages= 499–508 |year= 2008 |pmid= 18029348 |doi= 10.1074/mcp.M700325-MCP200 }}
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