| 词条 | Larry Sandler |
| 释义 |
Laurence Marvin Sandler (1929–1987) was a "leading Drosophila geneticist",[1] active during the mid-20th century. Sandler is best known for his work establishing and elucidating the phenomenon of meiotic drive. (Meiotic drive is when one copy of a gene is passed on to offspring more than the expected 50% of the time.) Sandler earned a B.S. at Cornell University and did his doctoral work with Ed Novitski at the University of Missouri, where he collaborated with Gerry Braver.[2] Braver and Sandler discovered that meiotic chromosomal loss was one driver of allelic variation in natural populations,[2] (Sandler & Braver 1954.[3]) a phenomenon coined "meiotic drive" in a follow-up paper by Sandler and Novitski.[2] (Sandler & Novitski 1957.[4]) Sandler also collaborated with Iris Sandler, his wife and fellow scientist, who also worked as a graduate student in Novitski's lab.[1] In 1956, Sandler briefly joined the Biology Division at Oak Ridge National Laboratory, where Sandler and Dan Lindsley worked on sperm dysfunction.[1] After joining the lab of Jim Crow at the University of Wisconsin, Sandler and Yuichiro Hiraizumi began working on segregation distortion, publishing several papers together.[5] Sandler moved to the University of Washington in 1962.[1] There he supervised numerous graduate students who joined the field, including Bruce Baker, Adelaide T. Carpenter, Ian Duncan, Barry Ganetzky, Larry Goldstein, Kent Golic, Jeff Hall, Scott Hawley, Jim Mason, John Merriam, Joe O'Tousa, Leonard Robbins, Paul Szauter, Bill Sullivan, Jon Tomkiel, and Glenn Yasuda.[1] Sandler was professionally active, involved in the founding of the Drosophila Research Conference, and transferring it to the Genetics Society of America.[1] He was also involved with other conferences, including the International Congress of Genetics, and as editor with numerous genetics journals, including Annual Review of Genetics and Genetics.[1] Sandler was married to fellow scientist Iris Sandler, who ultimately became a historian of science.[1] The couple had two children, Jack and Dee Sandler.[1] He died in 1987.[1] Significant papers
Awards and recognition
References
1. ^1 2 3 4 5 6 7 8 9 Dan Lindsley, [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1460553/pdf/10101152.pdf "Larry Sandler: Personal Recollections"] Genetics 151: 1233–1237 (April 1999) {{authority control}}{{DEFAULTSORT:Sandler, Larry}}2. ^1 2 Dan Lindsley, [https://www.jstor.org/stable/2462565 "Larry Sandler: The Father of Meiotic Drive"], The American Naturalist, Vol. 137, No. 3, pp.283-286 (March 1991). 3. ^Sandler & Braver 1954 4. ^Sandler & Novitski 1957 5. ^B. Ganetzky, "Yuichiro Hiraizumi and forty years of segregation distortion", Genetics (1999). 7 : 1929 births|1987 deaths|American geneticists|Cornell University alumni|University of Missouri alumni|University of Wisconsin–Madison faculty|University of Washington faculty |
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