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词条 Leucolysin
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Leucolysin
| EC_number = 3.4.24.6
| CAS_number = 72561-03-6
| IUBMB_EC_number = 3/4/24/6
| GO_code =
| image =
| width =
| caption =
}}Leucolysin ({{EC number|3.4.24.6}}, Leucostoma neutral proteinase, Leucostoma peptidase A) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Cleavage of Phe1-Val, His5-Leu, Ala14-Leu, Gly20-Glu, Gly23-Phe and Phe24-Phe bonds in insulin B chain as well as N-blocked dipeptides

This enzyme is isolated from the venom of the western cottonmouth moccasin snake (Agkistrodon piscivorus leucostoma).

References

1. ^{{cite journal | vauthors = Wagner FW, Spiekerman AM, Prescott JM | title = Leucostoma peptidase A. Isolation and physical properties | journal = The Journal of Biological Chemistry | volume = 243 | issue = 17 | pages = 4486–93 | date = September 1968 | pmid = 5684005 }}
2. ^{{cite journal | vauthors = Spiekerman AM, Fredericks KK, Wagner FW, Prescott JM | title = Leucostoma peptidase A: a metalloprotease from snake venom | journal = Biochimica et Biophysica Acta | volume = 293 | issue = 2 | pages = 464–75 | date = February 1973 | pmid = 4711816 | doi = 10.1016/0005-2744(73)90353-7 }}

External links

  • {{MeshName|Leucolysin}}
{{Metalloendopeptidases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 3.4.24

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