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词条 Leukotriene receptor
释义

  1. See also

  2. References

  3. External links

The leukotriene (LT) receptors are G protein-coupled receptors that bind and are activated by the leukotrienes. They include the following proteins:

  • Leukotriene B4 receptors (BLTRs) - bind to and are activated by LTB4:
    • BLT1 (Leukotriene B4 receptor 1) - {{Gene|LTB4R}}
    • BLT2 (Leukotriene B4 receptor 2) - {{Gene|LTB4R2}}
  • Cysteinyl leukotriene receptors (CysLTRs) - bind to and are activated by LTC4, LTD4, and LTE4:
    • CysLT1 (Cysteinyl leukotriene receptor 1) - {{Gene|CYSLTR1}}
    • CysLT2 (Cysteinyl leukotriene receptor 2) - {{Gene|CYSLTR2}}

The recently elucidated CysLTE, represented by GPR99/OXGR1, may constitute a third CysLTR.[1]

See also

  • Eicosanoid receptor
  • Oxoeicosanoid receptor
  • Prostaglandin receptor
  • Thromboxane receptor

References

1. ^{{cite journal | vauthors = Kanaoka Y, Maekawa A, Austen KF | title = Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand | journal = J. Biol. Chem. | volume = 288 | issue = 16 | pages = 10967–72 | year = 2013 | pmid = 23504326 | pmc = 3630866 | doi = 10.1074/jbc.C113.453704 | url = }}

External links

  • IUPHAR GPCR Database - Leukotriene receptors
  • {{MeshName|Leukotriene+Receptors}}
{{Transmembrane receptors}}{{G protein-coupled receptors}}{{Leukotrienergics}}{{biochemistry-stub}}

2 : Eicosanoids|G protein-coupled receptors

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