| 词条 | Ligneous conjunctivitis |
| 释义 |
| name = Ligneous conjunctivitis | synonyms = | image = | alt = | caption = | pronounce = | field = ophthalmology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} Ligneous conjunctivitis is a rare form of chronic conjunctivitis characterized by recurrent, fibrin-rich pseudomembranous lesions of wood-like consistency that develop mainly on the underside of the eyelid (tarsal conjunctiva).[1] It is generally a systemic disease which may involve the periodontal tissue, the upper and lower respiratory tract, kidneys, middle ear, and female genitalia.[2] It can be sight-threatening,[2] and death can occasionally occur from pulmonary involvement.{{citation needed|date=July 2012}} It has been speculated hola ligneous conjunctivitis may be a manifestation of IgG4-related disease (IgG4-RD) involving the conjunctiva.[3] PathogenesisHistopathological findings from affected humans indicate that wound healing is impaired due to a deficiency in plasmin-mediated extracellular fibrinolysis.[1] Episodes may be triggered by minor trauma, eye surgery, or by systemic events such as infections or antifibrinolytic therapy.[2] Histology shows amorphous subepithelial deposits of eosinophilic material consisting predominantly of fibrin.{{clarify|date=July 2012}} Diagnosis{{Empty section|date=December 2017}}TreatmentLigneous conjunctivitis may be managed by topical treatments of plasminogen,[1] topical and subconjunctival fresh frozen plasma,[1] and fibrinolytic therapy.[4] References1. ^1 2 3 {{Cite journal | last1 = Schuster | first1 = V. | last2 = Seregard | first2 = S. | title = Ligneous conjunctivitis | journal = Survey of Ophthalmology | volume = 48 | issue = 4 | pages = 369–388 | year = 2003 | pmid = 12850227 | doi=10.1016/s0039-6257(03)00056-0}} 2. ^1 2 {{cite web|title=Ligneous conjunctivitis|url=http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=97231|publisher=Orphanet|accessdate=July 21, 2012}} 3. ^{{cite journal |author1=Chiang Wei-Yu |author2=iu Ting-Ting |author3=Huang Wan-Ting |author4=Kuo Ming-Tse |date=9 September 2016 |title=Co-existing ligneous conjunctivitis and IgG4-related disease |url=http://www.ijo.in/article.asp?issn=0301-4738;year=2016;volume=64;issue=7;spage=532;epage=534;aulast=Chiang |journal=Indian Journal of Ophthalmology |volume=64 |issue=7 |pages=532–534 |doi=10.4103/0301-4738.190154 |pmid= 27609168 |pmc=5026081}} 4. ^{{cite web|title=Ligneous Conjunctivitis|url=http://www.images.missionforvisionusa.org/anatomy/2006/03/what-is-ligneous-conjunctivitis.html|publisher=Ocular Pathology|accessdate=July 21, 2012}} External links{{Medical resources| ICD10 = H10.4 | ICD9 = | ICDO = | OMIM = 217090 | DiseasesDB = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeSH = | GeneReviewsNBK = | GeneReviewsName = | Orphanet = 97231 }} 3 : Disorders of conjunctiva|Inflammations|IgG4-related disease |
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