The following is the filmography for Canadian actor, producer, screenwriter and director Michael Ironside.
| Year | Title | Role | Notes | | 1977 | Outrageous! | Drunk |
| 1978 | High-Ballin' | Butch |
| 1978 | Power Play | Torturer | Uncredited |
| 1979 | Summer's Children | Pimp |
| 1979 | Stone Cold Dead | Murdered Police Detective |
| 1979 | The Family Man | Bartender |
| 1980 | Deadly Companion | Edgar |
| 1980 | Suzanne | Jimmy |
| 1980 | Coming Out Alive | Gateway |
| 1981 | Scanners | Darryl Revok |
| 1981 | Surfacing | Wayne |
| 1982 | Best Revenge | Dealer |
| 1982 | Visiting Hours | Colt Hawker |
| 1983 | American Nightmare | Sgt. Skylar |
| 1983 | Adventures in the Forbidden Zone | Overdog |
| 1983 | Cross Country | Detective Sgt. Roersch |
| 1984 | The Cap | Steve's Father |
| 1984 | The Surrogate | George Kyber |
| 1984 | Terror in the Aisles | Darryl Revok | Archival footage |
| 1985 | The Falcon and the Snowman | Lead FBI Agent |
| 1986 | Jo Jo Dancer, Your Life Is Calling | Detective Lawrence |
| 1986 | Top Gun | LCDR Richard "Jester" Heatherly |
| 1987 | Extreme Prejudice | Major Paul Hackett |
| 1987 | Nowhere to Hide | Ben |
| 1987 | Prom Night II | Principal Billy "Bill" Nordham |
| 1988 | Office Party | Larry Gaylord |
| 1988 | Watchers | Lem Johnson |
| 1989 | Mindfield | Kellen O'Reilly |
| 1989 | Thunderground |
| 1989 | Destiny to Order | Kendrick |
| 1990 | Chaindance | J.T. Blake | Also screenwriter |
| 1990 | Total Recall | Richter |
| 1991 | The Quickening | General Katana |
| 1991 | Payback | Sheriff Pete |
| 1991 | McBain | Frank Bruce |
| 1991 | Neon City | Harry M. Stark |
| 1992 | Guncrazy | Mr. Kincaid |
| 1992 | Killer Image | Luther Kane |
| 1992 | The Vagrant | Lt. Ralf Barfuss |
| 1992 | Cafe Romeo | Natino |
| 1992 | Black Ice | Quinn |
| 1993 | Night Trap | Bishop |
| 1993 | Sweet Killing | Inspector Garcia |
| 1993 | Free Willy | Dial |
| 1993 | Father Hood | Jerry |
| 1993 | Point of Impact | Roberto Largo | aka Spanish Rose |
| 1994 | The Killing Machine | Mr. Green | aka The Killing Man |
| 1994 | Bolt | Billy Niles |
| 1994 | Tokyo Cowboy | Lyle |
| 1994 | Save Me | Oliver |
| 1994 | Fortunes of War | Carl Pimmler |
| 1994 | Forced to Kill | Sheriff Wilson |
| 1994 | Red Scorpion 2 | Colonel West |
| 1994 | The Next Karate Kid | Colonel Dugan |
| 1994 | Red Sun Rising | Captain Meisler |
| 1995 | Major Payne | Lt. Colonel Stone |
| 1995 | The Glass Shield | Detective Gene Baker |
| 1995 | Kids of the Round Table | Butch Scarsdale |
| 1996 | The Destiny of Marty Fine | Mr. Capelli |
| 1996 | Too Fast Too Young | Captain Floyd Anderson |
| 1996 | Portraits of a Killer | Sgt. Ernie Hansen |
| 1996 | One Way Out | Walt |
| 1997 | Chicago Cab | Al | aka Hellcab |
| 1997 | One of Our Own | Detective Jack Cooper |
| 1997 | Cold Night Into Dawn | Frank Parr |
| 1997 | Starship Troopers | Lt. Jean Rasczak |
| 1998 | Captive | Detective Briscoe |
| 1998 | Black Light | Inspector Frank Schumann |
| 1998 | Ivory Tower | Marshall Wallace |
| 1998 | Death Row the Tournament | Judge | Short film |
| 1998 | Going to Kansas City | Mike Malone |
| 1998 | Desert Blue | Agent Frank Bellows |
| 1999 | The Arrangement | Det. Francis John 'Jack' Connor | Also director and screenwriter; aka Blood Money |
| 1999 | Question of Privilege | Lt. Robert Ingram |
| 1999 | Southern Cross | Garrison Carver |
| 1999 | A Twist of Faith | Alex Hunt |
| 1999 | The Omega Code | Dominic |
| 2000 | Cause of Death | Jonas Phifer |
| 2000 | The Perfect Storm | Bob Brown |
| 2000 | Borderline Normal | Coach Rehmer |
| 2000 | Crime and Punishment in Suburbia | Fred Skolnick |
| 2000 | Nuremberg | Colonel Burton C. Andrus |
| 2001 | Down | Gunter Steinberg | aka The Shaft |
| 2001 | Revelation | Priest |
| 2001 | Ignition | Jake Russo |
| 2001 | Mindstorm | Senator Bill Armitage |
| 2001 | Dead Awake | Skay |
| 2001 | Extreme Honor | Baker |
| 2002 | Fallen Angels | Sheriff Ed Rooney |
| 2002 | Fairytales and Pornography | Justice Coulton |
| 2003 | The Failures | Depressor |
| 2003 | Maximum Velocity | General Amberson |
| 2004 | The Machinist | Miller |
| 2005 | Reeker | Henry |
| 2005 | Bloodsuckers | Muco | aka Vampire Wars: Battle for the Universe |
| 2005 | Guy X | Guy X |
| 2006 | Deepwater | Walnut |
| 2006 | 1st Bite | Theo |
| 2006 | The Veteran | Mark 'Doc' Jordan |
| 2008 | The Alphabet Killer | Captain Nathan Norcross |
| 2008 | Surveillance | Captain Billings |
| 2008 | Mutants | Colonel Gauge |
| 2009 | Terminator Salvation | General Hugh Ashdown |
| 2009 | The Butcher | Teddy Carmichael |
| 2009 | Level 26: Dark Origins | Tom Riggins | Short film |
| 2009 | The Jazzman | Bernie |
| 2009 | Hardwired | Hal |
| 2009 | The Beacon | Officer Ned Hutton |
| 2009 | Abduction of Jesse Bookman | Captain Jones |
| 2010 | The Bannen Way | Chief Bannen |
| 2010 | Eva | Alfonse |
| 2010 | Beneath the Blue | Blaine |
| 2011 | First Class | Captain of the 7th fleet |
| 2011 | Transgression | Matthew |
| 2011 | Conduct Unbecoming | Colonel Dodd |
| 2012 | All God's Children | Peter |
| 2013 | Ice Soldiers | Colonel Desmond Trump |
| 2013 | Stay | Frank |
| 2014 | Extraterrestrial | Travis |
| 2014 | A Fighting Man | Max Wynn |
| 2015 | Synchronicity | Klaus Meisner |
| 2015 | Desecrated | Tom McClain | Completed |
| 2015 | 88 | Sheriff Knowles |
| 2015 | The Sin Seer | Alexander Rachet |
| 2015 | Turbo Kid | Zeus |
| 2016 | Abysm | Doctor Julian Loro |
| 2016 | Children of the Fall | Sam |
| 2016 | Element | Joe |
| 2016 | Patient Seven | Dr. Daniel Marcus |
| 2017 | The Space Between | Nick |
| 2018 | Knuckleball | Jacob |
| Year | Title | Role | Notes | | 1978 | For the Record | Policeman | Episode: "A Matter of Choice" |
| 1979 | The Littlest Hobo | Bill | Episode: "Silent Witness" |
| 1983 | The A-Team | Miler Crane | Episode: "The Taxi Cab Wars" |
| 1983 | Hill Street Blues | Schrader | Episode: "Midway to What?" |
| 1984 | V: The Final Battle | Ham Tyler | Mini-series |
| 1984 | Mickey Spillane's Mike Hammer | Wade Bennett | Episode: "Warpath" |
| 1984–1985 | V: The Series | Ham Tyler | 13 episodes |
| 1985 | The Hitchhiker | Sheriff Lee | Episode: "Dead Man's Curve" |
| 1987 | Race for the Bomb | Werner Heisenberg | Mini-series |
| 1987 | Alfred Hitchcock Presents | Lt. Rick Muldoon | Episode: "Man on the Edge" |
| 1987 | Danger Bay | Charles Fuller | Episode: "Pilot Error" |
| 1988 | The Ray Bradbury Theater | Acton | Episode: "The Fruit at the Bottom of the Bowl" |
| 1990 and 1994 | Tales from the Crypt | Jerry / Burrows | 2 episodes - Season 2 (1990,) Episode: "The Sacrifice" (as Jerry;) Season 6 (1994 - 1995, episode aired in 1995,) Episode: "Comes the Dawn" (as Burrows) |
| 1995–2002 | ER | Dr. William 'Wild Willy' Swift | 7 episodes |
| 1995–1996 | seaQuest 2032 | Captain Oliver Hudson | 13 episodes |
| 1997 | The Series | Montree | Episode: "Get Fast" |
| 1998 | Witness to Yesterday | Vladimir Lenin | Episode: "Vladimir Lenin" |
| 1999 | Cold Squad | Chief Magnus Mulray | Episode: "Deadly Games: Part 1" |
| 1999 | The Outer Limits | Ambassador Prosser | Episode: "Summit" |
| 2000 | Walker, Texas Ranger | Nolan 'The Chairman' Pierce | 4 episodes |
| 2001 | The Outer Limits | General Quince | Episode: "Rule of Law" |
| 2002 | The Last Chapter | Bob Durelle | Mini-series |
| 2002 | The District | Dmitri Putin | 2 episodes |
| 2003 | The Last Chapter II: The War Continues | Bob Durelle | Mini-series |
| 2003, 2004 | Andromeda | The Patriarch | 2 episodes |
| 2004, 2010 | Smallville | General Sam Lane | 3 episodes |
| 2004 | Medical Investigation | Ben Graybridge | Episode: "Price of Pleasure" |
| 2005 | Young Blades | Cardinal Mazarin | 13 episodes |
| 2005, 2006 | Desperate Housewives | Curtis Monroe | 2 episodes |
| 2006 | Stargate SG-1 | Seevis | Episode: "Crusade" |
| 2006 | Masters of Horror | Mr. Chaney | Episode: "The V Word" |
| 2008 | Criminal Minds | John | Episode: "Elephant's Memory" |
| 2009 | Cold Case | Commandant Murillo | 3 episodes |
| 2010 | Castle | Victor Racine | Episode: "Den of Thieves" |
| 2010 | Burn Notice | Gregory Hart | Episode: "Friends and Enemies" |
| 2012 | Justified | Sarno | Episode: "Measures" |
| 2012 | R. L. Stine's The Haunting Hour | Margolin | 2 episodes |
| 2012 | Community | Lieutenant Colonel Norbert Archwood | Episode: "Basic Lupine Urology" |
| 2013 | Vegas | Porter Gainsley | 4 episodes |
| 2014 | Rake | Victor | Episode: "Three Strikes" |
| 2015 | The Flash | Lewis Snart | Episode: "Family of Rogues" |
| 2016 | Tokyo Trial | Douglas MacArthur |
| 2018 | The Alienist | J P Morgan |
| 2018 | This Is Us | Grandpa Pearson | Episode: "Vietnam" |
| 2019 | Hawaii Five-0 | Robert Castor | Episode: E'ao lu'au a kualima - Offer Young Yaro Leaves to |
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