Tame may refer to:

• Taming, the act of training wild animals
• River Tame, Greater Manchester
• River Tame, West Midlands and the Tame Valley
• Tame, Arauca, a Colombian town and municipality
• "Tame" (song), a song by the Pixies from their 1989 album Doolittle
• TAME (IATA code: EQ), flag carrier of Ecuador
• tert-Amyl methyl ether, an oxygenated chemical compound often added to gasoline.
• Tame.it, a context search engine for Twitter
• Tame, a variety of the Idi language of Papua New Guinea
• Tame (surname), people with the surname

• Thompson Engineering College
• Thompson Falls
• Thompson Falls High School
• Thompson Falls Montana
• Thompson Family
• Thompson Field
• Thompson Financial
• Thompson Fish House, Turtle Cannery and Kraals
• Thompson Garcia
• Thompson García
• Thompson, George
• Thompson gun
• Thompson hack
• Thompson, Hank
• Thompson Henry Murch
• Thompson (Heroes)
• Thompson H. Murch
• Thompson house
• Thompsonia
• Thompsonia (barnacle)
• Thompsonian medicalists
• Thompsonian medicine
• Thompson Island
• Thompson Island (Massachusetts)
• Thompson Island Outward Bound Education Center