B39 or B-39 may refer to:

• Bundesstraße 39, a German road
• B39 nuclear bomb
• XB-39 Superfortress
• Soviet submarine B-39, a Foxtrot class submarine
• HLA-B39, is an HLA-B serotype
• B39 (New York City bus)

• Tswapong Hills
• Tswapong language
• Tswapong people
• Tswaraganang
• Tswa-Ronga languages
• Tswa–Ronga
• Tswe
• Tswelelang
• T swift
• TS Windhuk (1936)
• TS Wisła Can Pack Kraków
• TS Woltmershausen
• TSW Pegasus FC
• TSX60
• TSX 60
• TSX (disambiguation)
• TSX:X
• Tsyarentjev
• Tsyarentjeva
• Tsyarentjew
• Tsyarentjewa
• Tsyarentsjev
• Tsyarentsjeva
• Tsyarentsjew
• Tsyarentsjewa